Amed M Tablet 2/500mg

Adult dose

This medication should be administered 1 to 2 times daily before or with meals. The dosage can be adjusted considering each patient’s current treatment regimen, efficacy, and tolerability, with appropriate blood sugar monitoring necessary. Typically, treatment starts at a low dosage, and adjustments are made based on the patient’s current medications and blood sugar levels. In clinical trials, the initial dosage was glimepiride/metformin hydrochloride 2mg/500mg, and blood sugar monitoring

This medication may cause severe lactic acidosis or hypoglycemia, and the risk is increased especially if renal function is significantly impaired. If signs of dehydration occur, this medication should be temporarily discontinued and the doctor should be informed. This medication should not be used in patients with renal function less than 45 mL/min/1.73m2, and if the renal function changes, administration should be stopped. Caution is needed when using this medication in patients at cardiovascular risk, as an increase in cardiovascular mortality has been reported. Patients with insulin-dependent diabetes, acute metabolic acidosis, severe liver impairment, pregnant or nursing women, and patients with moderate to severe renal impairment should not use this medication. In specific situations such as before and after surgery, severe infections, and malnutrition, administration of this medication should be temporarily stopped. During the initial course of treatment, there is a high risk of hypoglycemia, so blood sugar should be monitored carefully, and patients with irregular nutritional status or frequent alcohol consumption should also be cautious. This medication can cause gastrointestinal disturbances (diarrhea, nausea, vomiting, etc.), and these symptoms are generally temporary. Occasionally, skin rashes or allergic reactions may occur, and if symptoms are severe, immediate consultation with a doctor is advised. Long-term use may lead to vitamin B12 deficiency, so regular blood tests are necessary. Regular checks of renal function and blood sugar should be performed, and any abnormal symptoms during medication use should be reported to healthcare professionals immediately. This medication can interact with several drugs, so if taking other medications, it is essential to inform the doctor or pharmacist. During pregnancy or lactation, this medication should not be used, and other treatment methods should be employed for blood sugar control. Special caution is required when administering to children and elderly patients, and the elderly should have their renal function tested frequently. In case of overdose, hypoglycemia or lactic acidosis may occur, so if symptoms are suspected, immediate medical attention should be sought. During treatment with this medication, avoid alcohol consumption, and strive for blood sugar control through regular meals and exercise. Caution should be taken when driving or operating machinery due to the possibility of hypoglycemia or agility impairments.

Serious side effects

Hives, severe swelling (edema), shortness of breath, severe allergic reactions, lactic acidosis, acute renal failure, severe liver impairment, liver damage, liver failure, serious thrombocytopenia accompanied by thrombocytopenic purpura, hypoglycemia, cardiac arrest, rectal adenocarcinoma, severe skin adverse reactions, severe neurological symptoms (confusion, seizures, etc.), severe edema, urination abnormalities, jaundice, acute myocardial infarction, shock, pulmonary dysfunction, heart failure, cardiovascular

Mild side effects

Diarrhea, nausea, vomiting, abdominal distension, loss of appetite, indigestion, constipation, abdominal pain, gastrointestinal symptoms, temporary visual disturbances due to blood sugar changes, erythema, itching, rash, unpleasant metallic taste, vomiting, fullness or pressure in the upper abdomen, palpitations, dizziness, benign prostatic hyperplasia, indigestion, facial swelling, erectile dysfunction, hair loss, facial flushing, gastritis, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, granulocytopenia

This medication should be stored in a tightly closed container that allows for good air circulation, at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

White oblong film-coated tablet

Package unit

100 tablets (10 tablets/PTP X 10)