Rafugen 10 mg Tablets (Rafutidine)

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials of up to 8 weeks, most ulcers healed within 8 weeks, although healing time may occasionally vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials of up to 6 weeks, most ulcers healed within 6 weeks, although healing time may occasionally vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10 mg of lafutidine orally once daily before bedtime. In clinical trials of up to 2 weeks, most lesions healed within 2 weeks, although healing time may occasionally vary among patients. 4. Concomitant antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20 mg, clarithromycin 500 mg, and amoxicillin 1000 mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10 mg of lafutidine twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery), administered orally. 6. Treatment of reflux esophagitis: Administer lafutidine 10 mg twice daily.

This medication should not be used in patients who are allergic to any of its components. Furthermore, this medicine contains lactose, so patients with a genetic disorder that prevents proper digestion of lactose should avoid taking it. Patients with a history of drug allergies, liver or kidney function problems, those undergoing dialysis, and the elderly should use this medication cautiously. This drug can rarely cause serious allergic reactions, so if you experience facial pallor, a drop in blood pressure, or difficulty breathing, stop using it immediately and seek medical attention. It can affect liver function; if liver enzyme levels increase or jaundice symptoms appear, stop taking the medication and consult a doctor. There may be a decrease in blood cell counts, so if you experience symptoms like sore throat, fatigue, or fever, consult your doctor immediately. Rarely, symptoms such as skin rash, convulsions, and heart rhythm abnormalities have been reported; notify medical personnel if any unusual symptoms occur. Side effects such as abdominal pain, constipation, diarrhea, headache, dizziness, insomnia, and others may occur, so caution is advised. This drug may conceal symptoms of malignant tumors such as gastric cancer; therefore, if symptoms like weight loss, persistent vomiting, or hematemesis occur, you must get checked. Especially if gastric cancer is suspected, an early endoscopy and accurate diagnosis should be performed, and if confirmed as a malignant tumor, this medication should be discontinued. During treatment, the patient's condition should be carefully monitored, and if there is no effect, a different treatment method should be considered. The elderly should be cautious regarding dosage and administration intervals due to weakened physical function and should take it carefully. Dialysis patients may have higher blood concentrations of the drug, so they should start with a low dose and take it carefully. Pregnant women or women who may become pregnant should take this drug only if the benefits exceed the risks, as determined by a doctor, and breastfeeding women are advised not to take this medicine. Safety in children has not been established, so it is preferable to avoid use. This medication should be kept out of reach of children, and stored in its original container to prevent misuse or deterioration in quality.

• Shock
• symptoms of anaphylaxis
• pallor
• hypotension
• generalized pruritus
• dyspnea
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This drug should be stored in a tightly closed container to protect it from air and moisture, at a temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the medication's efficacy for a longer period.

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle