Seremed Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medication should be adjusted according to the patient and may be administered without regard to meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks at 400 mg per day, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea: The initially recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist for individuals who consume large amounts of alcohol daily. Taking this medication while drinking heavily can lead to serious problems such as gastrointestinal bleeding. Due to the risk of heart or vascular issues, it should be used at the lowest dose possible for the shortest duration. Even individuals without a history of cardiovascular disease should monitor symptoms closely, and immediate action should be taken if chest pain or shortness of breath occurs. Those with a history of gastrointestinal diseases or the elderly should be particularly cautious as ulcers or bleeding in the stomach may occur. If symptoms such as abdominal pain, indigestion, black stools, or vomiting blood arise, immediate medical attention is required. This medication is not used in individuals with specific allergies or severe liver, kidney, or heart dysfunction. Pregnant or nursing women should not take this medication. Individuals with asthma or allergic reactions should also avoid this medication. Regular checks of liver and kidney function and blood pressure are necessary during treatment, and if there are any abnormal signs, use should be discontinued. Dizziness or drowsiness may occur while taking this medication, so be cautious when driving or operating machinery. There may be potential interactions when taken with other medications, so it is important to inform the doctor or pharmacist. Women planning to conceive should consult a healthcare provider before taking this medication. The elderly should be monitored more closely as kidney and heart functions may weaken. Long-term use of this medication may cause infertility symptoms, so it is advisable to consult a doctor for extended use.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, abdominal distention, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesiculobullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disorder, albuminuria, cystitis, hematuria, dysuria, pollakiuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, appetite loss, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical muscle tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various parts, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, contact dermatitis, injection site reaction, skin nodules, headache, leg cramps, sensory impairment, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, angioedema, insomnia, appetite loss, increased appetite, depression, neuroirritability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infections, herpes simplex, wound infections, gingivitis, herpes, shingles, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic disease of the breast, thoracic neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostatic disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urine urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, phototoxic reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease nephropathy, female infertility, chest pain, thirst, ulcerative stomatitis, gastritis, allergies, low back pain, hyperlipidemia, hearing loss

This medication should be stored in a tightly closed container to prevent air and moisture ingress, in a cool place between 15 degrees and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

A white to pale yellow powder-filled capsule with yellow stripes on both the upper and lower parts.

Package unit

30 capsules/bottle, 100 capsules/bottle, 300 capsules/bottle