Ceremin Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medication should be adjusted according to the patient and may be administered without regard to meals. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks at 400 mg per day, another treatment option should be considered. Acute pain and primary dysmenorrhea: The initially recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be used with caution for individuals who frequently consume alcohol in quantities exceeding a certain amount daily, as it may increase the risk of gastrointestinal bleeding; it is advisable to consult a physician or pharmacist. Additionally, this medication may increase the risk of cardiovascular thrombotic events such as myocardial infarction and stroke, so it should be used at the lowest effective dose for the shortest duration possible, with careful observation even for individuals without a history of cardiovascular disease. This medication can result in serious gastrointestinal problems such as ulcers, bleeding, and perforation; therefore, older patients or those with a history of gastrointestinal disorders should consult healthcare professionals immediately if any unusual symptoms occur during use. This medication should not be administered to patients with particular allergy histories or significantly impaired liver or kidney function, as well as pregnant or nursing women. Patients with weakened liver or kidney function, asthma, heart failure, high blood pressure, and other conditions should be closely monitored when using this medication. Common side effects when taken include dyspepsia, diarrhea, headache, dizziness, hypertension, skin rash, etc. If severe symptoms occur, it is essential to consult a doctor immediately. This medication can interact with various other drugs, so it must be reported to healthcare providers if any other medications are being taken; adjustments in dosage or frequency may be necessary. Women who are pregnant or planning to become pregnant should consult a specialist before taking this medication, as it may affect reproductive capacity. Older adults are at a higher risk of decreased kidney and heart function, so special precautions are essential, and regular health monitoring is recommended. Blood tests and liver and kidney function tests should be performed regularly during the intake of this medication to monitor for any abnormalities, and if symptoms worsen, the medication should be discontinued promptly, and healthcare professionals should be consulted. In cases of overdose, symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding may appear. If overdose is suspected, it is necessary to visit a medical institution immediately for proper treatment. It should be kept in a safe place out of the reach of children, and transferring the medication to another container should be avoided to prevent deterioration in quality and risk of accidents.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbances, albuminuria, cystitis, hematuria, dysuria, polyuria, renal stones, urinary incontinence, urinary tract infection, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, kidney dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various regions, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, dermal nodules, headaches, leg cramps, sensory reduction, migraines, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicidal thoughts, anosmia, ageusia, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reactions, angioedema, insomnia, anorexia, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, worsening of epilepsy, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, candidiasis, genital candidiasis, otitis media, mastalgia, menopausal symptoms, fibrocystic breast disease, chest neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatocellular necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized pustular dermatitis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, glomerulonephritis with minimal changes, female infertility, chest pain, nausea, constipation, thirst, ulcerative stomatitis, gastritis, allergies, back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive RA factor, pneumonia, dyspnea, elevated ALT, hearing impairment, anaphylactic reactions, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, pulmonary embolism

This medication should be stored in a tightly sealed container to prevent air and moisture ingress, and it is best to keep it at room temperature between 15 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication.

Appearance

A hard capsule with yellow and white stripes filled with white to light yellow powder

Package unit

[Domestic] 30 capsules/bottle, 100 capsules/bottle [Export] 30 capsules (10 capsules/PTP x 3)