Rosuvastatin Calcium 20 mg

Adult dose

This medication can be taken at any time of the day, regardless of meals. The initial dosage is 5 mg once daily, and it is adjusted to a maintenance dose according to treatment goals. The maintenance dose is typically adjusted to 10 mg once daily for most patients. Dosage adjustments should be made every 4 weeks or more based on LDL cholesterol levels, treatment goals, and patient response, and the maximum dosage can be increased up to 20 mg once daily.

Child dose

The usual dosage range for pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years) is 5 mg to 20 mg taken once daily. The dosage may be adjusted according to each individual patient's treatment goals over intervals of 4 weeks or more.

This medication should not be administered to certain patients. For example, patients who are allergic to this medication, patients with severely impaired liver function, patients with muscle disorders, patients taking certain immunosuppressants, patients with severe kidney dysfunction, women who are pregnant or breastfeeding, and patients with genetic issues such as lactose intolerance should not take this medication. Moreover, liver function tests and muscle-related tests should be regularly performed before and during treatment with this medication, and if there are any liver diseases or hypothyroidism, those conditions should be treated first. If symptoms of muscle pain or weakness occur, patients should immediately inform their doctor and undergo necessary tests. This medication should be used cautiously in individuals who consume excessive alcohol or have a history of liver disease, as well as in the elderly or patients with reduced kidney function. In addition, the risk of muscle injury may increase when taken with certain medications, so patients should consult with their doctor or pharmacist regarding concomitant medications. During treatment, abnormal symptoms such as liver dysfunction, muscle pain, skin rashes, or allergic reactions may occur, so patients should immediately consult with medical professionals if these symptoms arise. Specifically, although rare, severe skin reactions or liver damage may occur, requiring caution. Women who are pregnant or planning to become pregnant should not take this medication, and if pregnancy is confirmed during treatment, it should be discontinued immediately. It is also safer for breastfeeding women not to take this medication. In the case of overdose, there is no specific antidote, so treatment should be symptomatic and liver function and muscle enzyme tests should be conducted to manage the condition. Lastly, this medication may cause dizziness, so caution is required when driving or operating machinery. It is important to promptly consult with medical professionals regarding any changes in health status or abnormal symptoms during treatment.

Serious side effects

Hives, allergic reactions including angioedema, chest tightness, difficulty breathing, respiratory distress, jaundice, hepatitis, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), acute renal failure, oliguria, thrombocytopenia, severe muscle weakness, ocular myasthenia, immune-mediated necrotizing myopathy, rhabdomyolysis, severe skin abnormal reactions, severe allergic reactions, severe edema, or urination difficulties.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• muscle pain
• weakness
• diarrhea
• itching
• hematuria

This medication must be stored in a tightly sealed container to protect it from air and moisture. Additionally, it is important to store it at room temperature between 1°C and 30°C to maintain its efficacy.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle