Rosuvastatin Calcium 5mg

Adult dose

Irrespective of meals, take 5 mg once daily as the initial dose. If greater reductions in LDL cholesterol are required, adjust to a maintenance dose of 10 mg once daily. The maintenance dose may be adjusted based on LDL cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more, with a maximum daily dose of 20 mg.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosing range is 5 mg to 20 mg once daily. The dosing should be adjusted individually based on the recommended treatment goals.

This medication should not be used in certain patients. For example, individuals who are allergic to this medication, those with severely impaired liver function, patients with muscle disorders, those with severely impaired kidney function, and pregnant or breastfeeding women should not take this medication. Furthermore, high doses of this medication are contraindicated in patients at high risk of muscle problems. This medication contains lactose, so individuals with genetic issues like lactose intolerance should avoid it. It is important to regularly monitor liver function and muscle condition while taking this medication. Patients who consume alcohol heavily or have a history of liver disease should exercise extra caution, and those with hypothyroidism or other specific diseases should receive treatment first. If symptoms such as muscle pain or weakness occur, immediate notification of healthcare personnel is advised, and the medication may be discontinued if necessary. Taking this medication with certain drugs may increase blood concentrations, increasing the risk of muscle damage, so it is essential to consult a physician before combining it with other medications. In particular, it is advisable not to combine it with fibrate class drugs. Women who are pregnant or may become pregnant should ensure they use appropriate contraceptive measures before taking this medication and should avoid it during pregnancy. Breastfeeding mothers should also avoid this medication as it may be passed into breast milk. In case of overdose, there is no specific antidote, so treatment should be symptom-based and liver function and muscle enzyme levels should be monitored regularly. Dizziness may occur during treatment with this medication, so caution is required when driving or operating machinery. Finally, this medication may show higher blood concentrations in Asians, which may necessitate dosage adjustments.

Serious side effects

Rash, allergic reactions including angioedema, Stevens-Johnson syndrome, eosinophilia and systemic symptoms of drug reaction (DRESS), rhabdomyolysis, immune-mediated necrotizing myopathy, severe muscle weakness, ocular muscle weakness, hepatitis, jaundice, fatal and non-fatal liver failure, acute kidney failure, oliguria, chest tightness, difficulty breathing, dyspnea, serious skin reactions, severe allergic reactions, etc.

Mild side effects

Headache, dizziness, constipation, nausea, abdominal pain, itching, myalgia, weakness, diarrhea, chest discomfort, loss of appetite, abdominal bloating, syncope, generalized pain, muscle cramps, gout, erectile dysfunction, fatigue, numbness, sensory abnormalities, joint pain, hematuria, thrombocytopenia, memory loss, peripheral neuropathy, cough, increased serum creatinine, increased ALT, increased AST, abnormal liver function tests, increased CK, elevated HbA1c and fasting blood sugar levels, etc.

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to maintain storage temperatures between 1 and 30 degrees Celsius.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle