Celecox 200 mg Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. Starting on the second day, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug increases the risk of gastrointestinal bleeding for people who consume excessive alcohol daily, so it is essential to consult a doctor or pharmacist. It may increase the risk of cardiovascular diseases, so it should only be used at the minimum dosage and for the shortest duration possible, and a healthcare provider should be informed immediately if cardiovascular symptoms occur. Ulcers or bleeding may occur in the gastrointestinal tract, particularly in the elderly or those taking it for a long time, so gastrointestinal symptoms should be monitored closely. It should not be taken by individuals with allergies to this medication or those with specific liver, kidney, or heart diseases, and it should not be used by pregnant or nursing women. Patients with impaired liver or kidney function, asthma, hypertension, or heart failure should use this medication with caution and require regular monitoring during use. Dizziness or drowsiness may occur while taking this drug; therefore, driving or operating machinery should be avoided. This medication may interact with other drugs, so any concomitant medications should be disclosed to healthcare providers. Women who are pregnant or planning to become pregnant should be cautious, as this medication may affect reproductive capacity, and it should be stopped immediately upon confirmation of pregnancy. Children and adolescents should not use this drug as safety and efficacy have not been established. The elderly may have reduced liver, kidney, or heart function, requiring careful monitoring and management. Regular blood tests and liver and kidney function tests should be conducted for those taking this drug long-term, and any abnormal symptoms should be reported to healthcare providers immediately. Overdosage may lead to nausea, vomiting, drowsiness, and gastrointestinal bleeding, requiring immediate medical attention for proper treatment. This drug should be kept out of reach of children and should not be transferred to another container for safety.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, damage, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, decreased appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthritis, skeletal anomalies, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various parts, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reaction, skin nodules, headache, leg cramps, tension hyperactivity, sensory reduction, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, exacerbation of allergies, allergic reaction, weakness, chest pain, fluid retention, generalized edema, facial edema, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, hepatic failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, microvascular lesion glomerulonephritis, menstrual disorders, female infertility, chest pain, anaphylactic reaction, hallucinations, vasculitis, pulmonary embolism, gastrointestinal bleeding, hepatitis

This drug should be stored in a tightly closed container to prevent air or moisture ingress, ideally in a cool place between 15 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and prevent degradation.

Appearance

A white to yellowish powder filled in white hard capsules with yellow bands on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle