Celebrex Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. Starting on the second day, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding for those who consume large amounts of alcohol daily, so it is essential to consult a doctor or pharmacist before taking it. This medication may increase the risk of cardiovascular conditions such as heart attack or stroke; therefore, it should be used at the lowest effective dose for the shortest duration possible. There may be a risk of ulcers or bleeding in the gastrointestinal tract, so special caution is necessary for those with a history of gastrointestinal diseases or for the elderly. There is a possibility of allergic reactions including skin rashes or, in severe cases, life-threatening skin conditions. Discontinue use immediately if any unusual symptoms occur. Patients with impaired liver or kidney function, heart disease, high blood pressure, or diabetes should have regular check-ups while taking this medication and should follow a doctor's instructions. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication, and it should be discontinued immediately if pregnancy is confirmed during use. It is advisable not to use this medication in children or adolescents as safety and efficacy have not been established. This medication may interact with other drugs, so inform your doctor or pharmacist of any other medications you are taking. Dizziness or drowsiness may occur during treatment; therefore, it is safer to avoid driving or operating machinery. Long-term use of this medication requires regular blood tests, as well as liver and kidney function tests. Consult medical personnel immediately if any unusual signs occur.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, bowel perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, increased frequency of urination, kidney stones, urinary incontinence, urinary tract infection, visual confusion, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal impairment, acute kidney injury, interstitial nephritis, headache, leg cramps, hypertonia, sensory deficits, migraine, neuropathic pain, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergic exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, septicemia, sudden death, anaphylactic-like reaction, angioedema, insomnia, decreased appetite, increased appetite, depression, neuroexcitability, sleepiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic change of the breast, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cyst, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, elevated ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hyperlipidemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, elevated alkaline phosphatase, weight gain, decreased appetite, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthrosis, skeletal anomalies, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fracture, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reaction, skin nodules, visual confusion, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal impairment, acute kidney injury, interstitial nephritis, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute kidney injury, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, chest pain, malaise, drowsiness, nausea, vomiting, epigastric pain, hypertension, acute kidney injury, respiratory depression, coma

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. Additionally, it should be kept at room temperature between 15 to 30 degrees Celsius, avoiding conditions that are too hot or too cold.

Appearance

A capsule filled with a white to pale yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle