Asafjang Enteric Coated Tablets 100mg (Aspirin)

Adult dose

Enteric coated tablets: 1 tablet once daily, taken before meals with adequate water. Enteric coated capsules: 1 capsule once daily, taken before meals with adequate water.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages a day, so consultation with a physician or pharmacist is necessary. Individuals who have experienced allergic reactions to this medication or other salicylate products should not take it. Persons with peptic ulcers or a history of them should not take this medication. Those who have experienced asthma attacks or have aspirin-induced asthma may be at risk if they take this medication. Patients with bleeding disorders such as hemophilia or those prone to bleeding should not use this medication. Patients with severe liver or kidney dysfunction, and those with severe heart failure should avoid using this medication. Patients taking methotrexate at doses above a certain level need to be cautious if combining this medication, as it may pose risks. This medication should not be taken in the third trimester of pregnancy, and pregnant or nursing women should use it cautiously after consulting a physician. Patients with kidney or cardiovascular issues, a history of liver disease, or blood disorders or allergies should also use this medication with caution. Special caution is needed when administering this medication to children under three years of age, the elderly, pre-operative patients, or patients taking anticoagulants. This medication can cause allergic reactions, skin rashes, and in severe cases, life-threatening skin conditions, so it should be discontinued immediately if any unusual symptoms occur. Gastrointestinal symptoms may include appetite loss, stomach pain, nausea, vomiting, and long-term use may lead to gastrointestinal bleeding or ulcers. Neurological symptoms may include dizziness, headaches, and tinnitus, so dosage adjustment or discontinuation may be necessary if symptoms are severe. It may affect liver and kidney function; therefore, if any abnormal symptoms occur, tests should be conducted, and appropriate measures should be taken. Due to an increased risk of Reye's syndrome in children under the age of 14 with chickenpox or influenza infection, it should be used cautiously. This medication is for symptom relief and does not treat the underlying cause, so it is advisable to use it in conjunction with treatment addressing the underlying cause. Regular blood tests and liver function tests should be conducted during prolonged use, and dosage adjustments or discontinuation may be necessary if abnormalities are detected. When used for acute conditions, dosages should be adjusted based on symptom severity, and long-term use of the same medication should be avoided. After administration, rapid decreases in body temperature or symptoms such as weakness and cold extremities may occur; thus, especially in children with high fever, the elderly, or those with chronic illnesses, careful observation is necessary. Infections may be masked, so appropriate antibiotics should be used in conjunction when treating inflammation caused by infections, and caution should be exercised. This medication increases the risk of bleeding; therefore, it should be discontinued or healthcare providers should be consulted before and after surgery, and caution is needed even for simple dental procedures. There are many interactions between this medication and others, so especially when combined with anticoagulants, hypoglycemic agents, and non-steroidal anti-inflammatory drugs such as ibuprofen, consultation with a physician is necessary. In early and mid-pregnancy, the use of this medication should be avoided whenever possible, and if necessary, should be limited to the minimum dosage and duration. In late pregnancy, serious side effects may occur for the fetus and mother, so it should never be taken. Women who are breastfeeding should avoid taking this medication as it may be passed into breast milk. Elderly patients may exhibit adverse reactions more easily, so starting with a lower dose while monitoring conditions is recommended. As enteric-coated tablets, care should be taken to avoid damaging the enteric coating, and it is preferable not to take them with specific preparations.

Serious side effects

• Hives, severe swelling (angioedema), chest tightness, difficulty breathing, shock, and anaphylactic symptoms, asthma attacks, severe allergic reactions.
• Severe rashes with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, Stevens-Johnson syndrome, Lyell syndrome (toxic epidermal necrolysis), exfoliative dermatitis, liver abnormalities (jaundice), liver failure, acute renal failure.
• Severe neurological symptoms (seizures, confusion, etc.), blood disorders (aplastic anemia

Mild side effects

Erythema, itching, nasal congestion, cardiovascular-respiratory disorders, rash, swelling, symptoms of rhinitis, conjunctivitis, loss of appetite, heartburn, stomach pain, nausea, vomiting, tinnitus, hearing loss, dizziness, headaches, excitation, transient liver damage due to increased liver transaminases, hyperventilation, metabolic acidosis, impaired platelet function (prolonged bleeding time), anemia, leukopenia, thrombocytopenia, eosinophilia along with systemic symptoms.

Drug interactions

This medication may increase the risk of bleeding when combined with other non-steroidal anti-inflammatory drugs and salicylates. Using doses of methotrexate greater than 15mg/week may decrease kidney function. Additionally, caution is advised when used with anticoagulants, ibuprofen, naproxen, and other non-steroidal anti-inflammatory drugs, thrombolytics, platelet aggregation inhibitors, hemostatics, and diabetes medications (insulin preparations, tolbutamide, etc.) and uricosurics.

This medication should be stored in a tightly closed container to prevent air and moisture ingress, and it is recommended to store it in a cool place at or below 25 degrees Celsius. This will help maintain the medication's efficacy and prevent degradation.

Appearance

White, round, enteric-coated film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle