Exfin Tablet 5/160mg (Amlodipine Besilate, Valsartan)

Adult dose

The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is advised to take it at the same time each day (e.g., in the morning). If blood pressure control is inadequate, switching between the dosages of 5/80mg, 5/160mg, and 10/160mg can be considered. For patients with renal impairment, dose adjustments are not needed for mild to moderate cases; however, for severe renal impairment...

Child dose

The safety and efficacy of this medication in pediatric patients under 18 years of age have not been established, and its administration is not recommended.

This drug may cause serious harm to the fetus and newborn during the 2nd and 3rd trimesters of pregnancy, therefore it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to the ingredients in this medication or similar drugs, pregnant or nursing women, patients with severe kidney or liver diseases, or those with a history of certain heart conditions or angioedema should not take this drug. Patients with sodium or fluid depletion should correct their conditions before taking this drug, and if symptoms of hypotension occur, they should lie down immediately and receive intravenous fluid therapy if necessary. Patients with high serum potassium levels should be especially cautious when taking this drug along with potassium supplements or potassium-sparing diuretics, and they should frequently monitor their potassium levels. Patients with kidney issues or those who have received a kidney transplant, as well as those with a history of angioedema, should be cautious when taking this medication; if symptoms of angioedema occur, they should stop taking the medication immediately. Patients with heart failure or following a myocardial infarction should closely monitor kidney function and symptoms while on this medication, and patients with acute myocardial infarction should be careful as this medication may exacerbate angina or myocardial infarction symptoms. Like other vasodilators, this medication should be used with caution in patients with certain heart valve diseases. Taking this drug with other medications that have similar effects may increase the risk of hypotension, worsening kidney function, and hyperkalemia, so it is advised to avoid combination therapy or to frequently check blood pressure and kidney function under a doctor's guidance. Use caution when driving or operating machinery as dizziness or fatigue may occur. In case of overdose, severe hypotension or cardiac dysfunction may occur, and immediate medical assistance is required. Additionally, this medication is not recommended for children as its safety and efficacy have not been established, while older adults may receive similar dosing as in general adults.

Serious side effects

Urticaria, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, dyspnea or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound general weakness, sudden severe headache, thunderclap headache, seizures, confusion, visual disturbances

Mild side effects

• Headache
• dizziness
• drowsiness
• paresthesia
• lightheadedness
• tinnitus
• tachycardia
• palpitations
• syncope
• orthostatic hypotension

Store this medication in a tightly sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature of between 1 to 30 degrees Celsius at room temperature.

Appearance

Dark yellow oblong film-coated tablet

Package unit

30 tablets/bottle