Nesina Act Tablet 25/30 mg

Adult dosage

This medication is administered once a day regardless of meals. The tablets should not be divided. The recommended starting doses are as follows: - For patients with no prior experience of diabetes medication treatment and difficulty in blood sugar control with monotherapy: administer 25 mg/15 mg. - For patients who have difficulty in blood sugar control with metformin monotherapy: administer 25 mg/15 mg. - For patients who have difficulty in blood sugar control with pioglitazone monotherapy: administer 25 mg/15 mg or 25 mg/30 mg.

This medication may put strain on the heart in some patients, potentially worsening or newly causing heart failure. Therefore, after starting or increasing the dosage of this medication, careful observation of symptoms of heart failure such as weight changes, shortness of breath, and swelling is necessary. Patients with heart failure or a history of heart failure should not take this medication and should immediately consult a doctor if symptoms occur. Moreover, this medication may cause fluid retention leading to edema, which may be associated with heart failure, so caution is needed. This medication should not be administered to patients with certain genetic diseases or severely impaired liver or kidney function, patients with bladder cancer, pregnant women, or women who may become pregnant. During administration, if there are any bladder-related symptoms such as hematuria or urinary disorders, patients should inform their doctor immediately. This medication can cause hypoglycemia, so caution should be exercised for symptoms of hypoglycemia when used in combination with glucose-lowering agents like insulin or sulfonylureas, and dosage adjustment may be necessary. Additionally, this medication may affect liver function, so liver function tests should be performed prior to administration, and if any abnormal liver function symptoms develop during usage, immediate consultation with medical personnel is required. For premenopausal women, this medication may induce ovulation and increase the risk of pregnancy, so proper contraception is recommended. If severe joint pain or blistering skin conditions occur while taking this medication, it must be reported to a doctor immediately and treated. The elderly, patients with deteriorating kidney function, those who consume excessive alcohol, and patients with poor nutritional status should use this medication with caution. Lastly, the safety and efficacy of this medication for children have not been established, and it is advisable for breastfeeding women to avoid its use.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (including excessive and rapid weight change, difficulty breathing, edema), angioedema, hives, Stevens-Johnson syndrome, severe skin adverse reactions, severe allergic reactions, severe edema or urination problems (gross hematuria, urinary disorders, urgency), acute pancreatitis, severe liver abnormalities (fatal and non-fatal liver failure, jaundice), severe neurological symptoms, severe respiratory problems (difficulty breathing, asthma exacerbation)

Mild side effects

• Nasopharyngitis
• back pain
• upper respiratory tract infection
• influenza
• hypoglycemia
• headache
• sinusitis
• muscle pain
• pharyngitis
• platelet abnormalities

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is best to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. Storing it this way will help to safely preserve the efficacy of the medication.

Appearance

Pink, biconvex round film-coated tablet

Package unit

28 tablets (7 tablets/PTP x 4), 100 tablets (10 tablets/PTP x 10)