Hurex Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be taken with or without food. Osteoarthritis (degenerative arthritis): Take 200mg of celecoxib once daily, or divide the dose into 100mg per dose twice daily. Rheumatoid arthritis: Take 100mg or 200mg of celecoxib per dose twice daily. Ankylosing spondylitis (AS): Administer 200mg of celecoxib per dose once daily, or divide the dose into 100mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400mg daily. If no effect is observed after 6 weeks of treatment with 400mg daily, another treatment method should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is 400mg of celecoxib; if necessary, an additional 200mg may be administered on the first day of treatment. Starting on the second day of treatment, administer the recommended dose of 200mg per dose twice daily as needed. In patients with moderate hepatic impairment (Child-Pugh ClassⅡ), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastric bleeding if taken by individuals who regularly consume three or more alcoholic drinks daily; therefore, it is essential to consult a physician or pharmacist. This medication may increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke, so it should only be used at the minimal effective dose and duration, and immediate consultation with medical personnel is necessary if cardiovascular symptoms occur. It can affect the gastrointestinal tract, resulting in gastric ulcers, bleeding, perforation, etc., so particular caution is advised for patients with a history of gastrointestinal disease or the elderly, and immediate treatment should be sought if symptoms of gastrointestinal bleeding occur. It should not be administered to patients with specific allergy histories, severe liver or kidney disease, active ulcers, cardiovascular diseases, pregnant or nursing women. Patients with impaired liver or kidney functions, asthma, heart failure, and hypertension require careful monitoring and dose adjustments when taking this medication. While taking this medication, various adverse reactions such as dyspepsia, headache, dizziness, hypertension, cough, vomiting, skin rash, etc., may occur, so it is crucial to inform healthcare professionals of any unusual symptoms. This medication can interact with several drugs, so it is essential to inform healthcare providers about any concurrent medications, especially with antihypertensives, anticoagulants, antidepressants, and diuretics when used in combination. Women who are pregnant or planning to become pregnant should avoid using this medication, and those who are breastfeeding should decide whether to take it after consulting a physician. Elderly patients are at higher risk for decreased kidney and liver functions, thus requiring more careful monitoring during use. Regular blood tests and liver and kidney function tests are recommended to check for any abnormalities while taking this medicine. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and stomach pain may occur; immediate medical attention should be sought for proper treatment. Keep this medication out of reach of children and do not transfer it to another container for safety.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, urinary frequency, nephrolithiasis, urinary incontinence, urinary tract infection, visual confusion, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine occult blood, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various areas, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, contact dermatitis, injection site reactions, skin nodules, headache, leg cramps, tension headache, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic exacerbation, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, insomnia, anorexia, increased appetite, depression, neuro excitability, drowsiness, fatal intracranial hemorrhage, hallucinations, epilepsy exacerbation, upper respiratory tract infections, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbated bronchospasm, dyspnea, laryngitis, pneumonia, epistaxis, voice disorders, vesicular dermatitis, dermatitis, nail diseases, photosensitivity reactions, pruritus, erythematous rash, maculopapular rash, skin diseases, skin dryness, increased sweating, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug-induced rash, acute generalized pustular rash, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, anaphylactic reaction, hallucinations, intracranial hemorrhage, aseptic meningitis, loss of taste, loss of smell

This medication should be stored in a sealed, airtight container and kept at a temperature between 15 to 30 degrees Celsius to ensure its effectiveness.

Appearance

Capsule filled with white to light yellow powder with a white outer casing

Package unit

30 capsules/bottle, 100 capsules/bottle