Celebrex Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or divide the dose into 100 mg per dose twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, another treatment method should be considered. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib; if necessary, an additional 200 mg may be administered on the first day of treatment. Starting on the second day of treatment, administer the recommended dose of 200 mg per dose twice daily as needed. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug may pose a risk of gastrointestinal bleeding if taken regularly by people who drink three or more alcoholic beverages per day, so it is essential to consult a doctor or pharmacist. This drug can increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke, so it should only be used for the minimum effective dose and for the shortest duration possible; if cardiovascular symptoms occur, you should inform your healthcare provider immediately. This drug can cause serious gastrointestinal side effects, such as ulcers, bleeding, or perforation, especially in elderly patients or those with a history of gastrointestinal disorders, so caution is needed when taking it. This drug should not be administered to patients with specific allergies, severe liver or kidney impairment, or pregnant or breastfeeding women, and consultation with healthcare providers is imperative if applicable. Patients with impaired liver or kidney function, congestive heart failure, hypertension, or asthma should use this drug cautiously and should be monitored regularly for their condition. Various adverse reactions may occur during the use of this drug; if symptoms such as indigestion, headache, dizziness, rash, swelling, or difficulty breathing appear, you should inform your doctor immediately. This drug may interact with other medications, so it's essential to inform your healthcare provider of any other medications being taken, particularly when combined with antihypertensives, anticoagulants, or antidepressants. Women who are pregnant or planning to become pregnant should not take this drug, and if pregnancy is confirmed, the medication should be discontinued immediately. This drug is not recommended for use in children and adolescents under 18 years of age due to established safety and efficacy concerns. Elderly patients are at higher risk of reduced liver, kidney, and heart function, so greater caution is warranted; they should start on a lower dose if they weigh less. Patients taking this drug for a long time should have regular blood tests and liver and kidney function tests, and if abnormalities are found, the medication may need to be discontinued. Overdosage can result in symptoms such as vomiting, drowsiness, and gastrointestinal bleeding, requiring immediate medical intervention. This drug should be kept out of reach of children and transferring it to another container is not recommended as it may adversely affect the quality.

Gastrointestinal bleeding, cardiovascular thromboembolic events, myocardial infarction, stroke, upper and lower gastrointestinal tract perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, hives, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased N-acetyl-β-D-glucosaminidase (NAG), positive urinary hematuria, positive urinary protein, renal dysfunction, acute kidney injury, interstitial nephritis, headache, leg cramps, tension hypertonicity, sensory reduction, migraine, neuralgia, neuropathy, sensory disturbance, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, backache, allergic exacerbation, allergic reaction, weakness, chest pain, fluid retention, generalized edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, septicemia, sudden death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute kidney injury, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, anaphylaxis, hallucinations, vasculitis, pulmonary embolism, gastrointestinal bleeding, hepatitis

This medication should be stored in a tightly closed container to prevent air exposure, and it is best to keep it at room temperature between 15 to 30 degrees Celsius. Storing it this way will help maintain the drug's efficacy over time.

Appearance

A white capsule with a yellow band filled with white to light yellow powder

Package unit

100 capsules/bottle, 30 capsules/bottle