Anacox Capsule 200mg (Celecoxib)

Adult dose

The minimum recommended dose of this medication should be adjusted according to the patient and may be administered with or without food. Osteoarthritis (degenerative arthritis): Administer celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. Rheumatoid arthritis: Administer celecoxib 100 mg or 200 mg per dose twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose as needed is 200 mg per dose twice daily. Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastric bleeding in individuals who regularly consume more than three alcoholic beverages a day; it is essential to consult a doctor or pharmacist. It may increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke, so it should only be used at the lowest effective dose and for the shortest duration, while being vigilant for symptoms even in those without a history of cardiovascular disease. Serious gastrointestinal issues such as ulcers, bleeding, or perforation may occur, especially in elderly patients or those with a history of gastrointestinal diseases; if symptoms such as epigastric pain, dyspepsia, black stools, or vomiting blood occur, seek medical attention immediately. This medication is contraindicated in patients with specific allergic histories, severe liver or kidney impairment, active peptic ulcers, heart failure, and in pregnant or lactating women. Patients with impaired liver or kidney function, or with a history of cardiovascular disease, hypertension, or diabetes should be more cautious when taking this medication, and regular monitoring as directed by a doctor is required. Various adverse reactions may occur, with common symptoms being dyspepsia, diarrhea, headache, dizziness, hypertension, edema, etc. In particular, if skin rash, itching, blistering, or severe allergic reactions occur, discontinue use immediately and contact a healthcare provider. This medication may interact with other drugs, so it is essential to inform your doctor or pharmacist of any other medications you are taking, especially when combined with antihypertensive agents, anticoagulants, antidepressants, or diuretics. Women who are pregnant or planning to become pregnant should consult a doctor before taking this medication, as it may affect reproductive ability. Dizziness or drowsiness may occur while taking this medication, so caution is advised when driving or operating machinery. Safety and efficacy of this medication in children and adolescents have not been established, so it is advisable not to use in these populations. Elderly patients have a higher likelihood of diminished kidney, liver, and heart function, so careful monitoring is necessary during administration. Regular blood tests and liver and kidney function tests should be conducted to check for abnormalities during treatment; if any abnormal findings are present, consult your medical provider immediately. Overdose may result in vomiting, lethargy, drowsiness, and gastrointestinal bleeding; if symptoms occur, seek appropriate medical treatment immediately. Store this medication out of reach of children and be cautious not to transfer it to another container, as this could lead to accidents or degradation of quality.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hyperactivity, insomnia, anxiety, delusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, tension, sensory diminishment, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lassitude, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash accompanied by eosinophilia and systemic symptoms, acute renal failure, hyponatremia, menstrual disorders, female infertility, chest pain, bullous dermatitis, dermatitis, nail disorders, photosensitivity reactions, petechiae, dandruff, drug rash accompanied by eosinophilia and systemic symptoms, hearing loss, ear disorders, otalgia, hearing impairment, elevated ALT, elevated AST, increased γ-GTP, elevated ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, osteoarthritis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon rupture, back pain, muscular rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic fasciitis, contact dermatitis, injection site reactions, skin nodules, ageusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infections, visual haze, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis

Store this medication in a tightly closed container to prevent exposure to air or moisture, and keep it in a cool place between 15 to 30 degrees Celsius. Storing it this way helps maintain its effectiveness longer.

Appearance

White capsule filled with white to pale yellow powder with yellow stripes on the top and bottom

Package unit

30 capsules/bottle