Olodipine Tablet 5/40 Milligrams (Amlodipine, Olmesartan Medoxomil)

Adult dose

This medication is administered once daily, with one tablet taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). The recommended dosage is as follows: - 5/20 milligrams: Administered to patients whose blood pressure is not adequately controlled by monotherapy with amlodipine 5 milligrams or olmesartan medoxomil 20 milligrams. - 10/20 milligrams: Administered to patients with blood pressure not adequately controlled by olmesartan medoxomil 20 milligrams.

Child dose

The safety and efficacy of this medication in pediatric patients under 18 years of age have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it must be discontinued immediately if pregnancy is confirmed. It should not be administered to patients with hypersensitivity to any of its components, those who are pregnant or breastfeeding, those with severe liver dysfunction or aortic stenosis, those with biliary obstruction, patients undergoing kidney dialysis, those in shock, and certain diabetic patients. Patients with fluid or salt depletion may experience low blood pressure when this medication is initially administered, so it should be administered with caution. This medication has a vasodilatory effect and should be used carefully in patients with severe aortic stenosis, obstructive coronary artery disease, and congestive heart failure. Patients with impaired renal function may experience worsening kidney function after starting this medication, so renal function should be monitored regularly. Patients with decreased liver function should also use this medication with caution and may require dosage adjustments depending on their liver function status. Side effects such as dizziness, headache, hypotension, edema, dyspepsia, and rash may occur, and if any unusual symptoms arise, they should consult a healthcare professional. Women who are pregnant or planning to become pregnant are advised to use alternative treatments that are confirmed to be safe instead of this medication. Breastfeeding women should stop breastfeeding or discontinue this medication, as it may be transferred to breast milk and affect the infant. The safety and efficacy of this medication have not been established in children under 18 years of age, and its use is not recommended. Elderly patients should start at a lower dose considering potential declines in liver, kidney, and heart function and comorbidities, and should be monitored closely. In cases of overdose, symptoms such as hypotension and increased heart rate may occur, and immediate medical attention should be sought. This medication should be stored in a tightly closed container to protect it from direct sunlight and humidity, and kept out of reach of children.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• severe allergic reactions
• severe skin adverse reactions
• angioedema
• acute renal failure
• liver abnormalities (jaundice)
• leukopenia
• thrombocytopenia

Mild side effects

Dizziness, headache, drowsiness, abnormal sensation, diminished perception, lightheadedness, palpitations, rapid heartbeat, hypotension, orthostatic hypotension, cough, nausea, vomiting, dyspepsia, diarrhea, constipation, dry mouth, upper abdominal pain, rash, muscle tension, limb pain, low back pain, frequent urination, erectile dysfunction, peripheral edema, swelling, pitting edema, fatigue, weakness, facial swelling, decreased blood potassium levels, increased blood creatinine levels, increased blood uric acid levels, and gamma-glutamyl transferase elevation.

This medication should be stored in a tightly closed container to protect it from air and moisture. It is best maintained at room temperature between 1 to 30 degrees Celsius.

Appearance

Light yellow, round, film-coated tablets

Package unit

30 tablets/Alu-Alu [10 tablets/Alu-Alu x 3]