Harbika Tablet 10/40 Milligrams

Adult dose

This medication is administered once daily with water without regard to meals. If possible, it is recommended to take it at the same time each day (e.g., in the morning). The recommended dosing is as follows: - 5/20 milligrams: for patients whose blood pressure is not adequately controlled by monotherapy with amlodipine 5 milligrams or olmesartan medoxomil 20 milligrams. - 10/20 milligrams: for patients whose blood pressure is not adequately controlled by olmesartan medoxomil 20 milligrams.

Child dose

Safety and efficacy in pediatric patients under 18 years have not been established.

This medication can cause serious harm or death to the fetus and newborn if taken during the second and third trimesters of pregnancy, therefore it should be discontinued immediately upon confirmation of pregnancy. This medication should not be used in individuals allergic to the active ingredients or similar components, pregnant or nursing women, patients with severe liver impairment, severe aortic stenosis, biliary obstruction, patients on kidney dialysis, patients in shock, certain diabetic patients, and patients with moderate or worse kidney impairment. In patients with hypotension due to fluid or salt depletion, hypotensive symptoms may occur, therefore, careful monitoring of the condition is required upon initial intake, and appropriate measures should be taken if hypotension develops. Patients with heart-related conditions such as aortic stenosis, obstructive coronary artery disease, and congestive heart failure should use caution as rapid vasodilation may lead to hypotension. For patients with reduced kidney function, kidney function may worsen, thus regular monitoring is needed, and patients with impaired liver function should also be monitored closely. Common side effects during treatment include dizziness, headache, low blood pressure, swelling, dyspepsia, and skin rash; however, severe side effects have also been reported, so immediate consultation with healthcare professionals is necessary upon the onset of unusual symptoms. This medication may interact with certain drugs, so inform your doctor or pharmacist if you are taking other medications, particularly avoiding co-administration with grapefruit juice. Use of this medication should be avoided during pregnancy and alternative safe treatments should be sought if pregnancy is planned or confirmed. There is a possibility that this medication may be excreted in breast milk and cause side effects in infants, so it is recommended to either discontinue breastfeeding or stop taking the medication. Use in pediatric patients under 18 years is not recommended as safety and efficacy have not been established. For elderly patients, it is advisable to start with a low dose considering potential decline in kidney and liver function, and to monitor for adverse reactions during treatment. In cases of overdose, hypotension and tachycardia may occur, so if overdose is suspected, immediate treatment in a medical institution should be sought. This medication should be stored out of reach of children and protected from moisture, heat, and direct sunlight.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthmatic attacks, respiratory distress associated with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, vision changes, paralysis, urination

Mild side effects

Dizziness, headache, drowsiness, sensory disturbance, decreased sensation, hypersensitivity reactions involving the immune system, hyperkalemia, decreased libido, palpitations, hypotension, orthostatic hypotension, cough, nausea, vomiting, dyspepsia, diarrhea, constipation, dry mouth, abdominal pain, rash, muscle tension, limb pain, lower back pain, increased urination, erectile dysfunction, peripheral edema, swelling, pitting edema, fatigue, weakness, facial swelling, decreased potassium levels in blood, increased creatinine levels in blood, blood

This medication should be stored in a tightly closed container to prevent air and moisture from entering. Additionally, the medication should be stored at room temperature, ideally between 1 and 30 degrees Celsius.

Appearance

Reddish-brown round film-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2)