Esomel 20 mg Tablet (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Long-term maintenance therapy to prevent recurrence in patients with esophagitis: 20 mg once daily - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: 20 mg once daily - As needed

Children's dosage

Adolescents aged 12 and above - Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: 1

This medication should not be administered to certain patients. Patients with hypersensitivity to this drug or its components, or who have experienced such reactions in the past, should not use it. Additionally, when used in combination with amoxicillin or clarithromycin for Helicobacter pylori eradication, patients allergic to penicillin or macrolide antibiotics should also not be given this medication. It is also safer to avoid using this medication in patients on certain cardiac drugs, antiviral agents, and in nursing women. When taking this medication, attention is needed as various side effects may occur. Digestive symptoms like headache, abdominal pain, diarrhea, nausea, and vomiting are commonly reported, while rare cases may include hematological abnormalities, allergic reactions, mental symptoms, skin rashes, and liver function abnormalities. Especially, if muscle pain or weakness occurs, serious conditions like rhabdomyolysis should be suspected and immediate medical consultation is required. Regular check-ups are necessary when taken for extended periods. This medication decreases stomach acid secretion which may increase the risk of bacterial overgrowth in the stomach, thus if diarrhea persists, you should consult a doctor. Additionally, long-term use may increase the risk of fractures, so patients at risk of osteoporosis should be cautious. There may be a decrease in magnesium levels, requiring periodic checks of serum magnesium levels especially when taken long-term or in combination with certain medications. This medication may interact with other medications, so if there are concurrent medications, it is essential to inform healthcare providers. Caution is particularly needed when used with drugs affecting blood coagulation, antiviral agents, some antibiotics, and anticonvulsants. During pregnancy, safety data for this medication is limited, thus pregnant women should be cautious and consult a physician prior to use. Nursing mothers are advised not to take this medication. In case of overdose, there is no specific antidote, so appropriate treatment according to symptoms and general management is necessary. Finally, this medication should be kept out of reach of children, and transferring it to another container is not advisable for maintaining quality.

Serious side effects

Angioedema, anaphylaxis, shock, urticaria, severe rashes with fever, blistering, skin peeling, pain in oral/ocular mucosa, bronchospasm, difficulty breathing, jaundice, hepatitis, liver failure, encephalopathy in patients with pre-existing liver disease, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), severe swelling, elevated blood pressure

Mild side effects

Headache, dizziness, sensory disturbances, drowsiness, taste disorders, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, renal interstitial nephritis, gynecomastia, weakness, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, back pain, chest pain, facial swelling

This medication may be weak against air or moisture, so it should be stored in a tightly sealed container. Additionally, it is important to store it at room temperature between 1°C and 30°C to maintain its effectiveness.

Appearance

Pale pink round film-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2)