Cecox Capsule 200 Milligrams (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered with or without food. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily or 100 mg twice daily in divided doses. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, consider another treatment. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day if needed. Starting on the second day, the recommended dose, if needed, is 200 mg twice daily. Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), reduce the dose to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three alcoholic drinks per day, so consultation with a physician or pharmacist is essential. This medication may increase the risk of thrombosis-related conditions such as cardiovascular diseases, myocardial infarction, and stroke; therefore, it is important to take it at the lowest effective dose and for the shortest duration necessary. Serious problems such as perforation, ulcer, and bleeding may occur in the gastrointestinal tract, so particular caution is advised for the elderly or those with a history of gastrointestinal disorders. Individuals with hypersensitivity or a history of specific allergies, those with severe liver or kidney impairment, and pregnant or nursing women should avoid taking this medication. Patients with reduced liver or kidney function, asthma, heart failure, hypertension, or those taking specific medications should use this drug cautiously and consult a physician before administration. While taking this drug, various side effects such as indigestion, vomiting, abdominal pain, headache, dizziness, skin rash, swelling, hypertension, etc., may occur; therefore, any abnormal symptoms should be reported to medical personnel immediately. As this drug is metabolized in the liver, taking it with other medications that affect liver function may cause changes in blood concentration, necessitating dosage adjustments. Particularly in late pregnancy, there is a risk of harm to the fetus, so women who are pregnant or may become pregnant should avoid taking this drug, and if pregnancy is confirmed while taking it, administration should be stopped immediately. Elderly patients are at higher risk for reduced kidney and heart function, so extra caution is needed during administration, with regular checks required to ensure no abnormalities occur. For long-term use of this medication, regular blood tests and kidney and liver function tests are necessary, and if any abnormal findings are observed, use should be discontinued immediately. In the case of an overdose, symptoms such as vomiting, drowsiness, and gastrointestinal bleeding may occur; therefore, appropriate treatment should be sought at a hospital immediately. Keep out of the reach of children and avoid transferring the medication to other containers, as this may compromise its quality.

Gastrointestinal bleeding, cardiovascular thrombosis, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, hemorrhage, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, headache, leg cramps, sensory impairment, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute renal failure, hyponatremia, cholelithiasis, jaundice, menstrual disorder, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholestasis, cholestatic hepatitis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, elevated alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle rigidity, reduced hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reaction, dermal nodules, taste disorders, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, blurred vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, interstitial nephritis, acute renal failure, vasculitis, anaphylactic reaction, hallucination, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, pneumonia, chest pain, facial swelling, nausea, diarrhea, insomnia, headache, dizziness, constipation, gastric ulcer, urticaria, anemia, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive RA factor, shingles, pneumonia, dyspnea, elevated ALT, hearing impairment

This medication should be stored in a tightly sealed container to prevent air ingress, and it is best to keep it at room temperature between 15 degrees Celsius and 30 degrees Celsius. This way, the medication’s effectiveness can be well maintained.

Appearance

White to slightly pale yellow powder in an opaque white hard capsule

Package unit

30 capsules/bottle, 100 capsules/bottle