Lodivica Tablet 2.5/20 mg (Escitalopram Nicotinate, Olmesartan Medoxomil)

Adult dose

This medication should be taken once daily, with or without food, along with water. It is recommended to take it at the same time each day (e.g., in the morning). The recommended dosing is as follows: - 2.5/20 mg: administered to patients whose blood pressure is not adequately controlled with 2.5 mg escitalopram (5 mg amlodipine) or 20 mg olmesartan medoxomil monotherapy. - 5/20 mg: for olmesartan medoxomil.

Child dose

Safety and efficacy have not been established for pediatric patients under 18 years.

This medication can cause serious harm to the fetus and newborn during the second and third trimesters of pregnancy, so if pregnancy is confirmed, it should be discontinued immediately. Patients with allergies to this medication or similar drugs, those who are pregnant or breastfeeding, patients with severe liver disorders, aortic stenosis, biliary obstruction, renal dialysis, shock, specific diabetes patients, and patients with renal impairment should not take this medication. Patients with fluid or salt depletion, those at risk of rapid vascular expansion, severe obstructive coronary artery disease, congestive heart failure, impaired renal function, and those with decreased liver function should use this medication with caution and be closely monitored. While taking this medication, side effects such as dizziness, headache, hypotension, edema, dyspepsia, rash may occur, and if symptoms persist, consult a doctor. This medication is not a beta-blocker, hence beta-blockers should be gradually reduced to avoid risks related to sudden cessation. When taken with other medications that can affect blood pressure control, regular monitoring of blood pressure, renal function, and electrolyte levels is required, particularly because of the risk of elevated potassium levels. Taking this medication during pregnancy can cause serious side effects in the fetus, so it should not be used during pregnancy, and if planning to conceive, a doctor should be consulted. During breastfeeding, this medication may be transmitted through breast milk, so it is advisable to either discontinue breastfeeding or stop taking the drug. Safety and efficacy have not been established for patients under 18 years of age, so it is not recommended. Elderly patients may have reduced renal and liver function, therefore should start from a low dose and be cautious during administration. In cases of overdose, severe hypotension, vascular expansion, and rapid heart rate may occur, so immediate medical attention is required.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa, wheezing or difficulty breathing, asthma attack, cough with fever and respiratory distress, yellowing of the skin or eyes (jaundice), extreme tiredness, sudden and severe headache, lightning-like headache, seizures, altered consciousness, visual disturbances, paralysis, urination.

Mild side effects

• Dizziness
• headache
• drowsiness
• paresthesia
• sensory loss
• lightheadedness
• palpitations
• fast heartbeat
• hypotension
• orthostatic hypotension

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. Proper storage can help maintain the drug's effectiveness over time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle