Lodivika Tablet 5/40 mg (Isamlodipine Nicotinate, Olmesartan Medoxomil)

Adult dose

This medication is administered once daily, 1 tablet with water regardless of meals. It is recommended to take it at the same time each day, if possible (e.g., in the morning). The recommended dosing regimen is as follows: - 2.5/20 mg: Administered to patients whose blood pressure is not adequately controlled with Isamlodipine 2.5 mg (Amlodipine 5 mg) or Olmesartan Medoxomil 20 mg monotherapy. - 5/20 mg:

Child dose

The safety and efficacy in pediatric patients under 18 years of age have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it must be discontinued immediately upon confirmation of pregnancy. This medication should not be taken by individuals who are allergic to any of the components or similar drugs, pregnant or nursing women, patients with severe liver disease or certain heart conditions, and those undergoing renal dialysis. Patients with fluid or sodium depletion may experience excessively low blood pressure when starting this medication, so their condition should be monitored closely. If blood pressure drops too low, appropriate treatment may be necessary. This drug has a vasodilatory effect and can cause acute hypotension or cardiac issues; therefore, patients with severe heart disease should be particularly cautious. Patients with reduced kidney function may experience further deterioration in renal function while taking this medication, necessitating regular monitoring. Patients with poor liver function should also use caution when taking this drug, and dosage adjustments may be needed. Side effects such as dizziness, headache, hypotension, edema, dyspepsia, skin rash, and others may occur, so any abnormal symptoms should be discussed with a physician. This drug can interact with other medications, particularly antihypertensives, diuretics, potassium supplements, certain antibiotics, and grapefruit juice, so caution is advised when taking them together. Women who are pregnant or planning to become pregnant should consider alternative treatments with established safety rather than this medication. Nursing mothers should be aware that this medication can pass into breast milk and may affect the infant, so they should cease breastfeeding or consult a doctor during treatment. This drug is not recommended for children under 18 years of age, as safety and efficacy have not been established. Elderly patients may have reduced liver, kidney, or heart function, so they should start at a lower dose and be monitored closely when taking this drug. Overdose of this medication can lead to severe hypotension and cardiac issues due to vascular dilation, so in case of overdose, immediate medical attention is required. This medication should be stored away from direct sunlight, humidity, and heat, and it is important to keep it out of reach of children.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, extreme drowsiness throughout the body, jaundice, palpitations, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, serious skin reactions, yellowing of the skin or eyes, sudden and severe headache, lightning bolt headache, seizures, confusion of consciousness, visual disturbances, paralysis, markedly reduced urine output, severe body swelling

Mild side effects

• Dizziness
• headache
• orthostatic hypotension
• drowsiness
• sensory abnormalities
• diminished perception
• lightheadedness
• palpitations
• rapid pulse
• hypotension

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is advisable to maintain a storage temperature between 1 and 30 degrees Celsius room temperature to preserve the drug's efficacy.

Appearance

Reddish-brown round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle