RUDIA Capsule 50mg (Dihydroartemisinin)

Adult dose

Adults: Administer 50∼100mg of diacerein orally in 1∼2 divided doses daily after meals. Adjust the dose appropriately according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used by patients with inflammatory bowel diseases, such as ulcerative colitis or Crohn's disease. Likewise, it is contraindicated in patients with bowel obstruction syndrome or unexplained abdominal pain. Additionally, individuals allergic to this medicine or any component included, especially Rhein derivatives, should not take it. Patients with liver disease or a history of liver problems are also advised against using this medication. It is not for use in children under 15 years of age. Since this product contains lactose monohydrate, it should not be taken by individuals with hereditary lactose intolerance, galactose intolerance, or glucose-galactose malabsorption. Patients with a history of small intestine or colon disease should use this medication cautiously, as should women who are pregnant or breastfeeding. Older adults aged 65 and above should use a reduced dosage. Patients with allergies or hypersensitivity to the color additive Yellow No. 5 (Sunset Yellow FCF) should also take caution. Digestive symptoms such as diarrhea, abdominal pain, and loose stools may occur with this medication, and long-term use may lead to severe problems like gastrointestinal bleeding, ulcers, and perforations. Skin reactions, such as itching, rashes, and eczema, are common. Liver function abnormalities may arise, and caution is needed if liver enzyme levels increase. When taking this medication for a long period, always follow a doctor's advice, as severe diarrhea may lead to dehydration or electrolyte imbalance, prompting discontinuation and physician consultation. It is advisable to avoid taking it with laxatives. Because of the risk of liver damage, if any symptoms of liver dysfunction arise, usage should be stopped immediately, and alcohol consumption should be limited. When taking this medication, antacids or salts containing calcium, magnesium, or aluminum can interfere with drug absorption; thus, these substances should be taken at least 2 hours apart. Caution is also warranted when used concomitantly with diuretics due to the increased diuretic effect, which could lead to dehydration or hypokalemia. Furthermore, caution is indicated if taken with cardiotonics due to the increased risk of arrhythmias. Women who are pregnant or breastfeeding should refrain from using this medication as animal studies have indicated delayed bone formation in fetuses. The drug can be transmitted in small amounts through breast milk, so it is recommended to avoid use while breastfeeding. Overdosage may result in severe diarrhea, necessitating treatment such as electrolyte replacement.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforations), pigmentation of the rectal mucosa, dehydration, fluid and electrolyte imbalance, itching, rash, eczema, elevated serum liver enzymes, hypokalemia, symptoms of liver damage, severe diarrhea

Store this medication in a tightly closed container to prevent exposure to air or moisture. It is recommended to keep the storage temperature between 1 degree and 30 degrees Celsius at room temperature to maintain the drug's effectiveness and safety over time.

Appearance

A hard capsule with a yellowish upper part and a pale yellow lower part containing a brownish powder

Package unit

30 capsules/bottle, 500 capsules/bottle