Celebrex 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted according to the patient and may be administered with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily or 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily or 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib; if necessary, an additional 200 mg may be administered on the first day of treatment. From the second day, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding in individuals who consume alcohol daily, thus it is essential to consult with a physician or pharmacist. This medication may increase the risk of cardiovascular thrombotic events such as heart attacks or strokes; therefore, it should be used at the lowest effective dose for the shortest duration and cardiovascular symptoms should be reported to a healthcare provider immediately. Serious issues such as perforation, ulceration, or gastrointestinal bleeding may occur, so special caution is required in individuals with gastrointestinal disorders or the elderly. If symptoms of gastrointestinal bleeding develop, immediate medical attention is required. Patients with allergies to this medication or those with specific liver, kidney, or heart diseases, as well as pregnant or breastfeeding women, should not take this medication. Patients with impaired liver or kidney function or those with conditions such as asthma, hypertension, or heart failure should use this medication cautiously and regular monitoring may be needed before and after use. During treatment, side effects such as headache, dizziness, dyspepsia, skin rashes, edema, hypertension, and cough may occur, and if symptoms are severe, consultation with healthcare providers is advised. There may be interactions with other medications, so if any other medications are being taken, it is crucial to inform healthcare providers, particularly when combining with blood pressure medications, anticoagulants, antidepressants, or antibiotics. Women who are pregnant or planning pregnancy should consult a physician before use, as this medication may affect reproductive capacity, and it should be avoided during pregnancy. Elderly patients may have reduced liver, kidney, and heart function, so careful observation and testing are necessary when taking this medication. For those taking this medication long-term, regular blood tests and assessments of liver and kidney function are required, and any unusual signs should prompt immediate cessation and consultation with healthcare providers. If dizziness or drowsiness occurs, driving or operating machinery should be avoided, and in cases of overdose, symptoms such as vomiting, diarrhea, increased blood pressure, and kidney failure may appear, necessitating immediate medical attention. This medication's safety and efficacy have not been established in children, so it is recommended not to use it, and it should be stored out of reach of children.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injuries, dyspepsia, abdominal pain, headache, vertigo, constipation, gastric ulcer, anemia, thirst, ulcerative stomatitis, gastritis, allergies, back pain, chest pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, RA factor positive, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing loss, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized pustular rash, exfoliative dermatitis, acute kidney failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, malaise, fluid retention, generalized edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, headache, dizziness, leg cramps, tension, decreased sensation, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbated bronchospasm, cough, dyspnea, laryngitis, pneumonia, nosebleeds, voice disorders, vesicular dermatitis, petechiae, rash, alopecia, dermatitis, nail diseases, photosensitivity reaction, pruritus, erythematous rash, papular rash, skin diseases, dry skin, increased sweating, urticaria, erythema multiforme, exfoliative dermatitis, mucous membrane syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reactions, skin nodules, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual haze, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, impaired renal function, acute kidney failure, interstitial nephritis

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture and kept in a cool place between 15 and 30 degrees Celsius.

Appearance

White to pale yellow powder filling in a white hard capsule with yellow stripes above and below.

Package unit

30 capsules/bottle, 300 capsules/bottle