Jevrex Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks at 400 mg per day, consider another treatment. 4. Acute pain and primary dysmenorrhea: The initially recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day if needed. Starting on the second day, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding if taken by individuals who consume excessive alcohol daily, hence consultation with a doctor or pharmacist is necessary. Additionally, this medication may increase the risk of cardiovascular issues such as heart attack or stroke, so it should be used at the lowest effective dose for the shortest duration. Individuals with a history of gastric ulcers or bleeding should be cautious as serious problems like gastric perforation or bleeding can occur when taking this drug. This medication should not be administered to patients with specific allergies, severe liver or kidney diseases, or to women who are pregnant or breastfeeding. Those with weak liver or kidney functions, asthma, heart failure, or high blood pressure should exercise caution and follow their doctor's instructions when using this drug. This medication can cause various side effects; if symptoms such as dizziness, indigestion, skin rash, or difficulty breathing occur during use, consult a healthcare professional immediately. There are many drug interactions, so any other medications being taken should be reported to a doctor, especially when used in conjunction with blood pressure medications, anticoagulants, or antidepressants. Women who are pregnant or planning to become pregnant should preferably not use this medication due to potential harm to the fetus, and breastfeeding mothers should be cautious as the drug can be transmitted through breast milk. The elderly may have decreased kidney and liver functions, so dose adjustments and monitoring are necessary when using this drug. For long-term use, regular blood tests and liver and kidney function tests should be conducted to check for abnormalities. In case of overdose, symptoms such as vomiting, drowsiness, and abdominal pain may occur, and immediate medical attention should be sought for appropriate treatment. Lastly, this medication should be kept out of the reach of children, and it is safe not to transfer it to another container.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, hemorrhage, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmias, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcers, dental diseases, duodenal ulcers, esophageal ulcers, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechial hemorrhage, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injuries, taste disturbances, albuminuria, cystitis, hematuria, dysuria, frequency of urination, nephrolithiasis, urinary incontinence, urinary tract infections, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, elevated CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, elevated alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon ruptures, pain in various regions, muscle stiffness, decreased hematocrit, increased hemoglobin, petechial hemorrhage, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, headache, hallucinations, aseptic meningitis, cerebral hemorrhage, anaphylactic reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, hepatic failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular rash, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, thirst, ulcerative stomatitis, gastritis, allergies, low back pain, hyperlipidemia, hearing loss, pneumonia, dyspnea

This medication should be stored in a tightly sealed container to prevent air ingress, and it is best stored in a cool place between 15 to 30 degrees Celsius. Storing it this way helps maintain the drug's efficacy for a longer period.

Appearance

A white to yellowish powder-filled, hard capsule with yellow stripes on its upper and lower parts.

Package unit

30 Capsules/Bottle, 100 Capsules/Bottle