Medication info
Myeongin Trazodone Hydrochloride Tablets 50 mg

Myeongin Trazodone Hydrochloride Tablets 50 mg

Prescription medicationTablet
Ingredient · strength
Trazodone Hydrochloride›50mg / 1 tablet
Manufacturer / importer
명인제약(주)
Appearance
Peach-colored round film-coated tablets
Packaging
100 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 201404400 · Approved 2014.09.26 · Insurance code 651904060

Summary

Main use
Improvement of depressive symptoms
Who uses it
Adults
Adult dosage
The initial dose of trazodone hydrochloride is 150 mg per day taken orally, increasing by 50 mg every 3 to 4 days. Outpatients should not exceed 400 mg per day, and hospitalized patients (severe depression) should not exceed 600 mg per day. Start at a low dose and gradually increase based on clinical response and tolerability. If drowsiness occurs, the majority of the dose should be taken at bedtime.

Ingredients

Manufacturer
명인제약(주)

Efficacy & effects

Improvement of depressive symptoms

  • Depression
View approved original text

This medicine is used for depression.

Dosage and Administration

Adult dosage

The initial dose of trazodone hydrochloride is 150 mg per day taken orally, increasing by 50 mg every 3 to 4 days. Outpatients should not exceed 400 mg per day, and hospitalized patients (severe depression) should not exceed 600 mg per day. Start at a low dose and gradually increase based on clinical response and tolerability. If drowsiness occurs, the majority of the dose should be taken at bedtime.

Precautions

This medication should be used cautiously in children, adolescents, and young adults with major depressive disorder or psychiatric disorders, as it can increase the risk of suicidal thoughts or behaviors. Additionally, persistent erection may occur during the use of this medication; if this happens, discontinue the medication immediately and consult a doctor. Persons allergic to this medication or its components, those taking MAO inhibitors for the treatment of certain mental disorders, children under 18 years of age, patients with acute myocardial infarction, those addicted to alcohol or sleeping pills, and patients currently taking certain other medications should not take this medication. Caution is necessary when using this medication in patients with heart disease, glaucoma, seizure disorders, bipolar disorder, psychosis, the elderly, those with a history of suicidal impulses, thyroid function abnormalities, or impaired kidney and liver function. This medication can cause a variety of side effects, such as severe muscle rigidity, fever, changes in blood pressure (neuroleptic malignant syndrome), blood abnormalities, hypersensitivity reactions, low blood pressure, psychiatric and neurological symptoms, gastrointestinal symptoms, and liver function abnormalities; consult a doctor immediately if any unusual symptoms occur. Drowsiness or decreased concentration may occur during use, so activities such as driving a car or operating dangerous machinery should be avoided, and blood tests should be performed if infection symptoms develop. This medication may interact with other drugs, particularly blood pressure medications, alcohol, central nervous system depressants, anticoagulants, certain antibiotics and antifungals, and serotonin-active drugs. Women who are pregnant or breastfeeding should carefully consider the risks and benefits of taking this medication; if breastfeeding, it is advisable to either avoid taking it or stop breastfeeding. In cases of overdose, symptoms such as drowsiness, vomiting, cardiac abnormalities, prolonged erection, and seizures may manifest, and appropriate treatment should be sought immediately.

Side effects

  • Motor paralysis
  • severe muscle rigidity
  • dysphagia
  • tachycardia
  • changes in blood pressure
  • sweating
  • fever
  • increased white blood cells
  • elevated serum creatine kinase
  • myoglobinuria
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  • decreased kidney function
  • high fever
  • altered consciousness
  • dyspnea
  • circulatory collapse
  • dehydration symptoms
  • acute renal failure
  • persistent erection
  • agranulocytosis
  • leukopenia
  • anemia
  • rash
  • pruritus
  • edema
  • hypotension
  • palpitations
  • hypertension
  • coma
  • hypopnea
  • syncope
  • bradycardia
  • increased suicidal tendency
  • agitation
  • delusions
  • hypersexuality
  • tremors
  • Parkinsonian symptoms
  • dizziness
  • stumbling
  • drowsiness
  • headache
  • heaviness in the head
  • insomnia
  • visual accommodation disorder
  • speech disorder
  • perception disorder
  • confusion
  • disorientation
  • incoordination
  • hyperactivity
  • ataxia
  • convulsions
  • excessive salivation
  • hallucinations
  • forgetfulness
  • anxiety
  • decreased concentration
  • nightmares
  • hostility
  • decreased libido
  • thirst
  • abdominal bloating
  • constipation
  • nausea
  • vomiting
  • loss of appetite
  • abdominal pain
  • diarrhea
  • sensation of heaviness
  • dysgeusia
  • elevated ALT
  • elevated AST
  • increased γ-GTP
  • fatigue
  • heat sensation
  • weakness
  • urinary disorders
  • nasal congestion
  • joint pain
  • muscle pain
  • sweating
  • tinnitus
  • urinary incontinence
  • frequent urination
  • ejaculation disorders
  • menstrual irregularities
  • chest pain
  • weight changes
  • fatigue
  • increased appetite
  • hematuria
  • erectile dysfunction
  • conjunctival congestion
  • eyelid itching
  • resting fatigue
  • drowsiness
  • decreased attention
  • decreased concentration
  • decreased reflex motor ability
  • nausea
  • headache
  • fatigue
  • anxiety
  • sleep disturbances
  • abnormal bleeding
  • hyponatremia
  • headache
  • concentration disorder
  • memory disorder
  • confusion
  • weakness
  • hallucinations
  • syncope
  • seizures
  • coma
  • respiratory arrest

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance and packaging

Appearance

Peach-colored round film-coated tablets

Package unit

100 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.