Celoix Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of taking 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg administered on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding if taken by individuals who consume large amounts of alcohol daily, so it is essential to consult a doctor or pharmacist. There is a risk of developing heart or vascular problems, so individuals with a history of cardiovascular disease or risk factors should use it with caution. Ulcers or bleeding in the gastrointestinal tract may occur, especially in the elderly or those with a history of gastrointestinal disorders, so symptoms should be closely monitored. This medication should not be administered to individuals with a history of specific allergies, severely impaired liver or kidney function, or women who are pregnant or breastfeeding. Patients with weaker liver or kidney function, asthma, heart failure, or hypertension should be carefully monitored when using this medication. While taking, various side effects like indigestion, headache, dizziness, skin rash, swelling, and difficulty breathing may occur, and immediate consultation with a doctor is required if severe symptoms arise. This medication may interact with other drugs, so you must inform your doctor of any medications you are taking, particularly when used with blood pressure medications, anticoagulants, and antidepressants. Pregnant women or those planning to become pregnant should avoid this medication, and those who are breastfeeding should also carefully consider whether to take it. It is advisable not to use this medication in children or adolescents, as safety and efficacy have not been established. The elderly may have decreased kidney, liver, and heart function, so extra caution should be observed when taking this medication. Regular blood tests and liver and kidney function tests are needed for individuals on long-term use, and usage should be discontinued if abnormalities are found. In case of overdose, symptoms such as vomiting, drowsiness, and gastrointestinal bleeding may occur, and immediate medical treatment is required. This medication should be stored out of reach of children and should not be transferred to other containers for safety.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, altered mental state, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, indigestion, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, bowel perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory disturbance, migraine, neuralgia, neuropathy, dysesthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, back pain, allergic exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, loss of appetite, increased appetite, depression, nerve hypersensitivity, drowsiness, fatal intracranial hemorrhage, hallucination, aggravation of epilepsy, upper respiratory infection, sinusitis, pharyngitis, rhinitis, bronchospasm, exacerbation of bronchospasm, dyspnea, laryngitis, pneumonia, nosebleed, voice disorder, vesicular dermatitis, dermatitis, nail disease, photosensitivity reaction, pruritus, erythematous rash, maculopapular rash, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, drug rash, arrhythmia, left ventricular hypertrophy, angina, unstable angina, coronary artery disorders, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, sinus bradycardia, fainting, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombotic phlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, necrosis, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, earache, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholecystitis, hepatitis, jaundice, hepatic failure, fulminant hepatitis, liver necrosis, increased sodium in the blood, increased potassium in the blood, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthropathy, skeletal abnormality, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fracture, tendon rupture, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reaction, skin nodules, gustatory dysfunction, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, kidney dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, anaphylactic reaction, hallucination, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized bullous fixed drug rash, fixed drug rash, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microangiopathic glomerulonephritis, female infertility

This medication must be stored in a tightly closed container to prevent exposure to air and moisture, and it is best kept in a cool place between 15 and 30 degrees Celsius. Storing it this way helps maintain the efficacy of the medication for an extended period.

Appearance

A white capsule with a yellow band on both ends, filled with a white to light yellow powder.

Package unit

100 capsules/bottle, 30 capsules/bottle