Celecoxib Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of taking 400 mg per day, other treatment options should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg administered on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three drinks per day, so it is essential to consult with a doctor or pharmacist first. There is an increased risk of cardiovascular disease, so it should be used at the lowest possible dose for the shortest duration, and if any cardiovascular symptoms occur, medical advice should be sought immediately. Severe problems such as perforation, ulcers, and bleeding in the gastrointestinal tract may occur, thus individuals with a history of gastrointestinal diseases or the elderly should take special precautions, and if gastrointestinal symptoms appear, they should seek medical attention right away. Individuals with hypersensitivity to this drug or with sulfonamide allergies, severe asthma, heart, kidney, or liver dysfunction, pregnant or breastfeeding women should not take this medication. Patients with impaired liver or kidney function, asthma, heart failure, hypertension, fluid retention, elderly individuals should use this medication cautiously, and periodic assessments are necessary. During treatment, various side effects such as headaches, dizziness, dyspepsia, vomiting, skin rashes, increased blood pressure, and edema may occur, so it is important to inform medical professionals of any unusual symptoms. Due to numerous interactions with other medications, especially when combined with drugs metabolized by the liver, antihypertensives, anticoagulants, and diuretics, the risk of kidney impairment or bleeding may increase; therefore, consultation with a doctor is vital. Pregnant women or those planning to become pregnant should avoid this medication, and nursing mothers should also refrain from taking it or stop breastfeeding. Safety for children and adolescents has not been established, so its use is not recommended. Elderly patients are more likely to have decreased kidney, liver, or heart function, requiring more caution during use, and dosage adjustments may be necessary. Long-term use should be monitored with regular blood tests and assessments of liver and kidney function. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and abdominal pain may occur, and immediate medical treatment is required. This medication should be kept out of reach of children, and it is safer not to transfer it to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, hemorrhage, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory loss, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, back pain, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, loss of appetite, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, epilepsy exacerbation, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchospasm, exacerbating bronchospasm, dyspnea, laryngitis, pneumonia, nosebleeds, speech disorders, vesicular dermatitis, dermatitis, nail disorders, phototoxic reactions, pruritus, erythematous rash, maculopapular rash, skin disorders, dry skin, hyperhidrosis, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash accompanied by eosinophilia and systemic symptoms, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microangiopathic glomerulonephritis, menstrual disorders, female infertility, chest pain, hearing loss, ear abnormalities, otalgia, hearing impairment, ALT elevation, increased serum sodium, increased serum potassium, elevated BUN, elevated CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, pyelonephritis, contact dermatitis, injection site reaction, skin nodules, gustatory dysfunction, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal impairment, interstitial nephritis

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is advisable to keep it at room temperature between 15 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness over time.

Appearance

A white capsule filled with a pale yellow powder with yellow stripes on the upper and lower parts.

Package unit

30 capsules/bottle, 300 capsules/bottle