Celebrex Capsule 200 mg (Celecoxib)

Adult dose

The lowest recommended dose of this medicine should be adjusted for each patient and may be administered without regard to meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. 2. Rheumatoid arthritis: Celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose is 200 mg twice daily as needed. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding if taken by individuals who consume a lot of alcohol daily, so it is essential to consult with a doctor or pharmacist. Caution is required for those with heart or vascular issues or risk factors, as this medication can increase the risk of cardiovascular diseases such as myocardial infarction or stroke. This medication can cause ulcers or bleeding in the stomach, so elderly patients and those with a history of gastrointestinal diseases should closely monitor gastrointestinal symptoms while taking it. Those who are allergic to this medication or have certain diseases (heart failure, severe liver and kidney diseases, peptic ulcers, etc.) should not take it. Individuals with compromised liver or kidney function, asthma patients, and those with high blood pressure should exercise particular caution when taking this medication and follow the doctor's directions. Regular checks of liver function, kidney function, blood pressure, etc., should be performed during the medication period to ensure there are no abnormalities. Dizziness or drowsiness may occur while taking this medication, so caution is advised when driving or operating machinery. It is safest for women who are pregnant or may become pregnant, as well as nursing mothers, to avoid taking this medication. Interactions with other drugs may occur, so anyone taking other medications should inform their doctor or pharmacist. Overdose may cause symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding, requiring immediate medical attention. The safety and efficacy of this medication have not been established in children and adolescents, so its use is not recommended. When storing this medication, keep it out of reach of children and do not transfer it to another container.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevation of liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, tension hypertonia, sensory reduction, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicidal behavior, anosmia, ageusia, allergic exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minor glomerular lesion nephritis, menstrual disorders, female infertility, chest pain, vesicular dermatitis, dermatitis, nail disease, photosensitivity reactions, pruritus, erythematous rash, maculopapular rash, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, skin-mucosa syndrome, toxic epidermal necrolysis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, folliculitis, contact dermatitis, injection site reactions, skin nodules, ageusia, albuminuria, cystitis, hematuria, dysuria, polyuria, renal stones, urinary incontinence, urinary tract infection, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, hallucinations, hearing loss, ear abnormalities, otalgia, hearing impairment, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, bile duct obstruction, bile duct obstruction hepatitis, jaundice, pneumonia, herpes zoster, herpes simplex, bacterial infection, fungal infection, soft tissue infection, moniliasis, genital moniliasis, otitis media, vasculitis, angioedema, anaphylactic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minor glomerular lesion nephritis, menstrual disorders, female infertility, chest pain

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, and the storage temperature should be maintained between 15 and 30 degrees Celsius. This helps preserve the medication's efficacy and prevents degradation.

Appearance

A white capsule filled with a white to light yellow powder.

Package unit

30 capsules/bottle, 100 capsules/bottle