Ranibis Tablets

Adult dosage

Typically, administer 2 tablets orally, twice a day before meals and at bedtime, regardless of meals. 1) Gastric and duodenal ulcers: Administer either 2 tablets twice a day or 4 tablets once a day at bedtime. For duodenal ulcer patients, 4 tablets can be given twice a day, morning and at bedtime. 2) Gastroesophageal reflux disease: Administer 2 tablets twice a day for 8 weeks or 4 tablets once a day at bedtime.

This medication should not be used in patients undergoing dialysis or in those with kidney function issues. Additionally, it should not be administered to patients who have had allergic reactions to this medication or its components, have a history of acute porphyria, have undergone upper gastrointestinal surgery, are pregnant or may become pregnant, are premature infants or newborns, or are on a dietary regimen that restricts potassium intake. Caution should be taken when administering this medication to patients with liver dysfunction, a history of drug allergies, the elderly, those with a history of kidney disease, and patients taking non-steroidal anti-inflammatory drugs concurrently. Particularly, since it may mask symptoms of gastric cancer, it should be used in patients with gastric ulcers or new digestive symptoms occurring in those aged 40 and above only after malignancy has been ruled out. Patients with helicobacter pylori infections need bacterial eradication therapy, and caution should be exercised when using this medication in patients in severe intensive care or with hypophosphatemia and dysphagia. Rarely, anaphylactic shock, skin rash, urticaria, or angioedema may occur, and if symptoms appear, administration should be stopped immediately, and appropriate treatment should be received. Blood tests may reveal leukopenia, thrombocytopenia, or hepatic dysfunction; if abnormal symptoms arise, administration should be halted, and testing should be done. Symptoms such as cardiac arrhythmias, nausea, vomiting, constipation, diarrhea, headache, dizziness, drowsiness, confusion, agitation, insomnia, and headache may occur, and medical consultation should be sought if these symptoms appear. Avoid long-term use, and if treatment effects are not observed, consider switching to another medication, especially in the elderly or chronically ill patients, as there may be an increased risk of pneumonia. It is advisable to avoid driving or operating dangerous machinery while taking this medication. Additionally, this medication can interact with other medications, so if there are other concomitant drugs, be sure to inform healthcare professionals, paying particular attention to anticoagulants or certain antibiotics. Pregnant or breastfeeding women should not take this medication, and its safety in children has not been established, so it is best not to administer it to them. In cases of overdose, treatments such as vomiting or gastric lavage may be necessary, and regular check-ups, including ophthalmologic examinations, are recommended for long-term users.

Serious side effects

Urticaria, severe swelling (including angioedema), tightness in the chest, difficulty breathing, shock (anaphylactic shock), severe allergic reactions, severe skin reactions (including mild erythema multiforme), jaundice hepatitis, non-jaundice hepatitis, hepatic dysfunction (including jaundice), sudden and severe headaches, seizures, altered consciousness, visual disturbances, paralysis, rhabdomyolysis, severe swelling of the body accompanied by increased blood pressure.

Mild side effects

• Skin rash
• angioedema
• fever
• bronchospasm
• low blood pressure
• chest pain
• granulocytopenia
• leukopenia
• thrombocytopenia
• elevated serum enzyme levels

Store this medication in a tightly closed container to prevent air from entering, ideally at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle