Altirizine Tablets (Levocetirizine Hydrochloride)

Adult dose

Adults and children over 6 years: take 1 tablet (5 mg of levocetirizine hydrochloride) orally once daily, regardless of meals. Adjust according to age and symptoms. For patients with renal impairment, adjust dosage based on renal function (estimated glomerular filtration rate [eGFR]). - Normal renal function (≥ 90 mL/min): 1 tablet once daily. - Mild renal impairment (60 -< 90 mL/min): 1 tablet once daily.

This medication should not be used in patients who are allergic to specific components or have hypersensitivity to hydroxysine or piperazine derivatives. Patients with end-stage renal disease or those undergoing hemodialysis should not take this medication. It should not be administered to infants under 1 year, and children under 6 years should receive it in liquid form rather than as tablets. This tablet contains lactose, so patients with lactose intolerance or related genetic disorders should not use this medication. Patients with renal or liver function impairment, as well as the elderly, should take this medication cautiously, as its concentration may increase. Drowsiness, fatigue, headache, dizziness, and other central nervous system symptoms may occur during treatment, so caution is advised when driving or operating machinery. Gastrointestinal symptoms such as nausea, abdominal pain, and diarrhea may also occur. Rare side effects such as heart palpitations, blood abnormalities, allergic reactions, and blurred vision have been reported. Drowsiness or lethargy may occur after taking this medication, so caution is required, and taking it with alcohol or central nervous system depressants may exacerbate these symptoms. Patients with urinary excretion disorders or epilepsy should use this medication cautiously as their condition may worsen. Pregnant women should take this medication according to their doctor’s instructions due to limited safety data, and breastfeeding women should be cautious as this medication may be secreted in breast milk and could cause adverse reactions in the infant. Children and the elderly may require dose adjustments due to decreased kidney function which could lead to increased drug concentrations. This medication may affect the results of allergy tests; it is advisable to discontinue it before testing. In case of overdose, symptoms such as drowsiness, agitation, and restlessness may occur, and as there is no specific antidote, treatment should be symptomatic. This medication is difficult to remove by hemodialysis.

Serious side effects

• Urticaria
• severe swelling (edema)
• angioedema
• anaphylactic shock
• hypertension
• respiratory distress

Mild side effects

• Drowsiness
• lethargy
• headache
• numbness
• agitation
• drowsiness
• fatigue
• dizziness
• heaviness
• excitement

This medication should be stored in a tightly closed container that can block light, at a temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness for a longer period.

Appearance

White or pale yellow oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle