Medication info
Esoprol Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Esoprol Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Prescription medicationTablet
Ingredient · strength
Esomeprazole Magnesium Trihydrate›44.5mg / 1 tablet
Manufacturer / importer
명문제약(주)
Appearance
Pink round film-coated tablet
Packaging
28 tablets/box [(14 tablets/PTP*2)]
Approval status
Active

MFDS item code 201403490 · Approved 2014.07.29 · Insurance code 649806680

Summary

Main use
Treatment of gastroesophageal reflux disease (including erosive esophagitis), treatment and prevention of recurrence of Helicobacter pylori positive peptic ulcer, relief of gastrointestinal symptoms associated with non-steroidal anti-inflammatory drugs and prevention of gastric ulcers.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If not cured or if symptoms persist, an additional 4 weeks of usage is required. - Maintenance therapy for the prevention of recurrence of esophagitis: 20 mg once daily. - Treatment of gastroesophageal reflux disease symptoms without esophagitis: 1 dose once daily,
Children's dosage
Adolescents aged over 12 years - Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist, an additional 4 weeks of usage is required. - Esophagitis

Ingredients

Manufacturer
명문제약(주)

Efficacy & effects

Treatment of gastroesophageal reflux disease (including erosive esophagitis), treatment and prevention of recurrence of Helicobacter pylori positive peptic ulcer, relief of gastrointestinal symptoms associated with non-steroidal anti-inflammatory drugs and prevention of gastric ulcers.

  • Gastroesophageal reflux disease
  • erosive esophagitis
  • esophagitis
  • duodenal ulcer
  • peptic ulcer
  • upper gastrointestinal symptoms
  • pain
  • discomfort
  • burning sensation
  • gastric ulcer
  • duodenal ulcer
  • Zollinger-Ellison syndrome
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease and erosive esophagitis, and for long-term maintenance therapy to prevent recurrence in patients with esophagitis. It also helps prevent recurrence of duodenal and peptic ulcers when combined with antibiotics for the eradication of Helicobacter pylori. It is effective in treating symptoms such as pain, discomfort, and burning sensation in the upper gastrointestinal tract caused by non-steroidal anti-inflammatory drugs, and is used in the treatment and prevention of gastric and duodenal ulcers related to these drugs. Additionally, it is used for the treatment of Zollinger-Ellison syndrome and for maintenance therapy to prevent rebleeding of gastric or duodenal ulcers after intravenous administration. Overall, it is widely used for the treatment of various symptoms and diseases related to gastrointestinal disorders.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If not cured or if symptoms persist, an additional 4 weeks of usage is required. - Maintenance therapy for the prevention of recurrence of esophagitis: 20 mg once daily. - Treatment of gastroesophageal reflux disease symptoms without esophagitis: 1 dose once daily,

Children's dosage

Adolescents aged over 12 years - Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist, an additional 4 weeks of usage is required. - Esophagitis

Precautions

This medication should not be used by individuals with certain allergic reactions or those who have previously had allergies to this medication or similar ingredients. The side effects may worsen when taken with certain antibiotics or other medications, so it should not be combined without consulting a physician. Regular blood tests or other examinations should be conducted during the use of this medication, and special caution is required for long-term use. If unusual symptoms or severe side effects occur during administration, inform medical personnel immediately, and be cautious as severe allergic reactions or skin abnormalities may occur. This medication can reduce stomach acid, increasing the risk of bacterial infections in the gastrointestinal tract, so if diarrhea or abdominal pain persists, consult medical personnel. In patients with osteoporosis or those on long-term use, the risk of fractures may increase, so it's advisable to regularly monitor bone health status. This medication can interact with other drugs, so inform medical personnel about all medications being taken, especially with anticoagulants, antiviral drugs, and antibiotics. If pregnant or breastfeeding, consult a physician before using this medication, and breastfeeding individuals should avoid this medication for safety. In case of overdose, there is no specific antidote, so immediate medical attention is required, and it should be kept out of the reach of children to prevent accidents.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, anaphylactic reaction, shock, hypomagnesemia, hypocalcemia, hypokalemia, mental confusion, jaundice, hepatitis, liver failure, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalised exanthematous pustulosis, eosinophilia with systemic symptoms drug reaction (DRESS syndrome), interstitial nephritis, severe edema, muscle weakness, rhabdomyolysis, severe allergic reactions, myocardial infarction

Mild side effects

Headache, dizziness, sensory disturbances, drowsiness, taste disorder, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, increased liver enzymes, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, weakness, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, chest pain, facial swelling, flushing, fatigue, fever, malaise, pain, stiffness, peripheral edema

Not everyone experiences these, and they can vary from person to person.

Storage

This medicine should be stored in a sealed container to protect it from air and moisture. It is recommended to store it at room temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Pink round film-coated tablet

Package unit

28 tablets/box [(14 tablets/PTP*2)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.