Leadpen Plus Soft Capsule (Dexibuprofen)

Adult dose

Administer 300 mg of dexibuprofen orally 2 to 4 times a day. However, do not exceed 1,200 mg of dexibuprofen in one day.

This drug may pose a risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic drinks a day; therefore, it should be discussed with a doctor or pharmacist. This medication can affect the cardiovascular system and may increase the risk of severe thrombotic events such as myocardial infarction or stroke. Caution is particularly advised for individuals with cardiovascular diseases or risk factors, and it is essential to consult a physician promptly if any cardiovascular symptoms arise during use. Moreover, this medication can burden the gastrointestinal tract, potentially causing serious gastrointestinal adverse reactions such as bleeding, ulcers, and perforation. Elderly patients and those with a history of gastrointestinal disorders should consider this carefully before use, and report any abnormal symptoms immediately to healthcare personnel. It is safer not to take this medication for individuals with a history of gastrointestinal ulcers or bleeding, severe liver or kidney impairment, heart failure, hypertension, or asthma. During treatment, it should not be used concomitantly with aspirin, other non-steroidal anti-inflammatory drugs, or high-dose methotrexate, as it may increase the risk of side effects. While taking this medication, breastfeeding should be discontinued or discussed with a physician, and caution should be exercised while driving or operating machinery due to possible dizziness or fatigue. Individuals with blood abnormalities, impaired liver or kidney function, hypertension, heart failure, hypersensitivity history, elderly patients, and children (6 years and older) must consult with a physician or pharmacist before use. Should shock, severe skin rash, breathing difficulty, severe gastrointestinal symptoms, liver dysfunction, or worsening kidney function occur during treatment, stop taking the medication immediately and consult with healthcare personnel. This drug should be taken at the minimum effective dose for the shortest duration necessary, with regular blood tests and monitoring of liver and kidney function required during long-term use. It is advisable to avoid use during pregnancy, especially after six months, as it may pose risks to the fetus, and if this medication is necessary during pregnancy, thorough consultation with a physician is required. In cases of overdose, even if symptoms are absent, it is important to seek medical attention promptly, and keep it out of the reach of children, avoiding direct sunlight, and storing it in a cool, dry place.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in the oral or ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, disorientation, visual disturbances, paralysis, urinary issues.

Mild side effects

• Dyspepsia
• abdominal distension
• heartburn
• upper abdominal pain
• diarrhea
• constipation
• loss of appetite
• nausea
• vomiting
• abdominal pain

Drug interactions

Do not take this medication with aspirin or other non-steroidal anti-inflammatory drugs. Do not use in combination with high doses (more than 15 mg/week) of methotrexate used for chemotherapy. Use caution with corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors, angiotensin II receptor antagonists, diuretics, lithium, and anticoagulants of the coumarin type (such as warfarin).

Store this medicine in a tightly closed container to prevent exposure to air or moisture, and it is recommended to keep it at room temperature between 1 and 30 degrees Celsius.

Appearance

Orange transparent oval soft capsule containing translucent yellow to light orange oily contents.

Package unit

10 capsules per box [(10 capsules / PTP × 1)]