Olmesartan Medoxomil 10 mg Tablets

Adult dose

The recommended initial dose is 10 mg once daily, administered regardless of meals. If blood pressure is not adequately controlled, it may be increased to 20 mg once daily. The dose may be increased up to a maximum of 40 mg once daily. The antihypertensive effect appears within 2 weeks after treatment initiation and reaches maximum effect around 8 weeks. If blood pressure is not controlled, it may be administered in combination with thiazide diuretics such as hydrochlorothiazide.

This medication can cause serious harm to the fetus and newborn when administered to pregnant women in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients allergic to any ingredient in this medication, pregnant or lactating women, patients on dialysis, patients with severe liver dysfunction, patients with biliary obstruction, and certain genetically predisposed lactose intolerant patients should not take this medication. Patients with decreased blood volume or salt may experience hypotension when taking this medication, so their condition should be carefully monitored, and appropriate measures should be taken immediately if hypotension occurs. Patients with severe congestive heart failure or impaired kidney function may experience further deterioration of kidney function when taking this medication, so it should be administered with caution. Patients with poor kidney function or kidney transplant patients should have their blood potassium and creatinine levels monitored regularly when taking this medication, and it is not recommended for patients with severe kidney dysfunction. Patients with aortic or mitral stenosis or obstructive or hypertrophic heart disease require special attention when taking this medication. There is a risk of hyperkalemia, so patients with heart failure or kidney impairment should frequently check their blood potassium levels. Dizziness may occur while taking this medication, therefore, activities requiring alertness, such as operating dangerous machinery or driving, should be avoided. This medication is primarily used for the treatment of hypertension and has been shown to have a tolerability similar to that of a placebo in clinical trials, with side effects generally being mild and transient. The most common side effect is dizziness, while other possible effects include headache, back pain, dyspepsia, palpitations, and rash. Serious side effects such as angioedema, abnormalities in liver function, hyperkalemia, and acute renal failure have been reported, so patients should consult healthcare professionals immediately if unusual symptoms occur. Taking this medication in combination with other antihypertensive agents may enhance the blood pressure-lowering effect, and combining it with potassium-sparing diuretics or potassium supplements may dangerously elevate blood potassium levels. Co-administration with lithium formulations may pose a risk of lithium toxicity, so it is advisable to avoid such combinations. Combined use with non-steroidal anti-inflammatory drugs may increase the risk of renal function deterioration, so caution is needed. Should a pregnant woman take this medication, there are significant risks such as decreased kidney function in the fetus, reduced amniotic fluid, and the development of anomalies, so it must be discontinued immediately upon confirmation of pregnancy. Lactating women should consider stopping breastfeeding or discontinuing the medication, as this drug may be passed into breast milk. Safety and efficacy in pediatric patients have not yet been established, so this drug should be administered to children with caution. Elderly patients may have elevated drug concentrations, requiring dosage adjustment and careful monitoring of their condition. In case of overdose, symptoms such as hypotension and palpitations may occur, requiring immediate treatment. This medication does not pose a carcinogenic risk, even with prolonged use, and has been confirmed as safe in genotoxicity tests.

Serious side effects

Urticaria, angioedema, anaphylactic reactions, intestinal vascular edema, rhabdomyolysis, hyperkalemia, acute renal failure, elevated blood creatinine, urticaria, liver function abnormalities (increased liver enzymes and bilirubin levels), severe edema, elevated blood pressure, facial swelling, chest pain, asthma, epistaxis

Mild side effects

• Dizziness
• headache
• palpitations
• back pain
• hematuria
• hyperglycemia
• hypertriglyceridemia
• influenza-like symptoms
• pharyngitis
• rhinitis

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. The storage temperature should be in a cool place between 1 and 25 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle