Vasartan Plus Tablet 160/12.5 mg

Adult dose

The recommended adult dosage is 1 tablet of Valsartan 80 mg/Hydrochlorothiazide 12.5 mg once daily, taken with a small amount of water regardless of meals. For blood pressure reduction, the prescribed dosage of Valsartan 160 mg/Hydrochlorothiazide 12.5 mg should be applied. For patients with renal impairment classified as mild to moderate (creatinine clearance over 30 mL/min), dosage adjustment is not necessary.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, and should be discontinued immediately upon confirmation of pregnancy. Patients who have hypersensitivity to any component of this medicine or a history of certain hepatic disorders, renal disorders, or angioedema should not use it. Patients with certain conditions such as electrolyte imbalance, impaired renal function, liver dysfunction, diabetes, or heart failure should use this medication with caution, and elderly patients should also be monitored carefully. This medication may cause dizziness or drowsiness, so caution is needed when driving or operating machinery. Potassium supplements or potassium-containing foods should not be taken without consulting a doctor, and healthcare providers should be notified immediately if symptoms related to low blood pressure occur. Regular monitoring of renal function and electrolyte levels is essential while using this medication. The hydrochlorothiazide component may react sensitively to sunlight, requiring sunblock and skin protection, and any skin abnormalities should be reported immediately. There may be interactions with other medications, so consult a doctor particularly when using it with lithium, NSAIDs, or potassium-sparing diuretics. It is advisable to avoid using this medication during pregnancy or breastfeeding, and breastfeeding should also be discussed with a specialist. Safety and efficacy for children have not been established, so it is recommended not to use it in this population. In case of overdose, symptoms such as low blood pressure, arrhythmias, and electrolyte imbalances may occur, requiring immediate medical attention.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, symptoms resembling anaphylaxis, angioedema, hepatitis, renal failure, hyperkalemia, hyponatremia, shock, syncope, loss of consciousness, agranulocytosis, leukopenia, thrombocytopenia, aplastic anemia, hemolytic anemia, necrotizing vasculitis, toxic epidermal necrolysis (Stevens-Johnson syndrome), interstitial pneumonia, pulmonary edema, exacerbation of systemic lupus erythematosus, hypoglycemia, rhabdomyolysis, angioedema.

Mild side effects

• Headache
• dizziness
• nasopharyngitis
• fatigue
• back pain
• cough
• upper respiratory tract infection
• diarrhea
• arthralgia
• abdominal pain

This medication is sensitive to air and moisture and should be stored in a tightly sealed container. Additionally, it is best stored at a cool temperature below 30 degrees Celsius.

Appearance

Dark red oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle