Medication info
Paramet 10 mg (Rabeprazole Sodium)

Paramet 10 mg (Rabeprazole Sodium)

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›10mg / 1 tablet
Manufacturer / importer
하나제약(주)
Appearance
Light yellow-pink round enteric-coated tablet
Packaging
28 tablets (14 tablets/PTP X 2)
Approval status
Active

MFDS item code 201403217 · Approved 2014.07.18 · Insurance code 657805310

Summary

Main use
Relief of symptoms of gastric ulcers and gastroesophageal reflux disease and treatment of Helicobacter pylori infection
Who takes it
Adults
Adult dose
Gastric ulcer, duodenal ulcer: Administer 10 mg orally once daily. Depending on symptoms, 20 mg may be taken once daily. Administer for up to 8 weeks for gastric ulcers, and up to 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms do not improve, additional 10 mg or 20 mg may be administered orally twice daily for 8 weeks.

Ingredients

Manufacturer
하나제약(주)

Efficacy & effects

Relief of symptoms of gastric ulcers and gastroesophageal reflux disease and treatment of Helicobacter pylori infection

  • Gastric ulcers
  • duodenal ulcers
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • symptoms of gastroesophageal reflux disease
  • gastrointestinal ulcers due to Helicobacter pylori infection
  • Zollinger-Ellison syndrome
View approved original text

This medication is used for the treatment of gastric ulcers and duodenal ulcers, effective for the relief of symptoms of erosive or ulcerative gastroesophageal reflux disease, and for long-term maintenance therapy. Additionally, it is used in combination with antibiotics for patients with gastrointestinal ulcers caused by Helicobacter pylori infection and also helps in the treatment of Zollinger-Ellison syndrome. Therefore, it is used for the treatment and symptom relief of various gastrointestinal conditions.

How to take

Adult dose

Gastric ulcer, duodenal ulcer: Administer 10 mg orally once daily. Depending on symptoms, 20 mg may be taken once daily. Administer for up to 8 weeks for gastric ulcers, and up to 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms do not improve, additional 10 mg or 20 mg may be administered orally twice daily for 8 weeks.

Precautions

This medication should not be used in patients with allergic reactions or hypersensitivity to any specific ingredients or to the drug itself. Particular caution is required for those with allergies to penicillin or macrolide antibiotics, and hypersensitivity to the antibiotics used in conjunction with this medication for the eradication of Helicobacter pylori should also be taken into account. It is safest for pregnant or breastfeeding women not to take this medication. Patients with impaired liver function or the elderly are at increased risk of side effects, and thus the drug should be administered with caution. This medication may cause allergic symptoms such as skin rash, itching, or hives; if such symptoms occur, the patient should stop taking it immediately and consult a physician. Regular blood tests or liver function tests are recommended during treatment, and the medication should be discontinued if any abnormalities are found. Side effects may occur in various areas including the heart, gastrointestinal tract, nervous system, skin, and respiratory system, so if symptoms arise, the patient should consult healthcare personnel immediately. Long-term use may increase the risk of osteoporosis and fractures, so bone health tests should be conducted if necessary. This medication may interact with other drugs, so patients should inform their healthcare provider about any other medications they are taking. Particularly caution should be exercised when combining it with drugs that affect blood coagulation, antiviral agents, and antibiotics. There may be drowsiness or dizziness when driving or operating dangerous machinery; caution should be practiced in these activities. There is no specific antidote for overdose; treatment should be symptomatic, and the tablets should be swallowed whole without chewing or crushing. Keep out of reach of children and do not transfer to other containers. Long-term use of this medication may cause vitamin B12 absorption disorders; nutritional status should be monitored as needed. If symptoms resembling systemic lupus erythematosus appear on the skin or systemically, stop taking this medication immediately and seek specialist care. Additionally, this medication may slightly increase the risk of gastrointestinal bacterial infections by suppressing gastric acid secretion, so if diarrhea or infection symptoms persist, the patient should visit a hospital.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, rash, blistering, skin peeling, pain in mouth/eyes mucous membranes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and severe headache, thunderclap headache, seizures, confusion of consciousness,

Mild side effects

  • Rash
  • hives
  • itching
  • decreased red blood cells
  • decreased white blood cells
  • increased white blood cells
  • increased eosinophils
  • increased neutrophils
  • decreased lymphocytes
  • anemia
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  • petechiae
  • lymphadenopathy
  • hypopigmented anemia
  • pancytopenia
  • agranulocytosis
  • decreased platelets
  • hemolytic anemia
  • ALT elevation
  • AST elevation
  • ALP elevation
  • γ-GTP elevation
  • LDH elevation
  • elevated total bilirubin
  • hypertension
  • myocardial infarction
  • ECG abnormalities
  • migraine
  • syncope
  • angina
  • heart block

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage ensures that the drug's efficacy is maintained and it can be used safely.

Appearance and packaging

Appearance

Light yellow-pink round enteric-coated tablet

Package unit

28 tablets (14 tablets/PTP X 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.