Neurocare Tablet 10 mg (Donepezil Hydrochloride Hydrate)

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before bedtime. If weird dreams, nightmares, or sleep disturbances occur, consider administering it in the morning. After administering 5 mg for 4 to 6 weeks and evaluating the clinical response, it may be increased to 10 mg. When increasing to 10 mg, administer cautiously while monitoring for gastrointestinal adverse reactions. Underweight elderly females should not exceed 5 mg per day.

Child dose

No experience in pediatric use.

This medication contains Donepezil Hydrochloride and is used to alleviate symptoms of Alzheimer's dementia. First, this medication should not be used in patients who are allergic to Donepezil Hydrochloride, piperidine derivatives, or any other components of this medication. Additionally, it is advisable that pregnant women, women who may become pregnant, and nursing mothers do not take this medication. Since this medication contains lactose, patients with lactose intolerance or genetic metabolic abnormalities such as galactose intolerance should avoid taking it. Patients with heart disease should use this medication cautiously. This medication may slow the heart rate or cause arrhythmia. Patients who are taking nonsteroidal anti-inflammatory drugs or have a history of peptic ulcers should be cautious due to the risk of gastrointestinal bleeding or worsening of ulcers. Patients with asthma or obstructive pulmonary disease should also be cautious as this medication may induce bronchoconstriction. Patients with extrapyramidal disorders, such as Parkinson's disease, should be careful as this medication may worsen symptoms. Moreover, patients with allergic reactions to the yellow #5 dye contained in this medication should inform their healthcare provider before taking it. Various side effects have been reported for this medication; in severe cases, symptoms such as fainting, heart problems, gastrointestinal bleeding, liver dysfunction, stroke, seizures, and muscle symptoms may occur. Commonly, nausea, vomiting, diarrhea, dizziness, insomnia, headache, and fatigue may frequently manifest. If serious side effects or unusual symptoms occur, consult a doctor immediately. This medication is approved solely for patients with Alzheimer's dementia and is not recommended for other forms of dementia or memory decline. Treatment should be conducted under the supervision of an experienced physician, and treatment effects should be regularly evaluated to consider discontinuation if necessary. Additionally, this medication may cause cardiac conduction issues, so patients with heart disease or a history of QT interval prolongation should have their condition checked through electrocardiograms while taking it. This medication is metabolized in the liver; therefore, patients with impaired liver function should use it with caution, and be mindful of potential dizziness or drowsiness when driving or operating machinery. Pregnant women or nursing mothers are advised not to take this medication; if necessary, it should be decided after consulting an expert. This medication may interact with other drugs; therefore, patients taking heart medications, antibiotics, antidepressants, antipsychotics, or anti-inflammatory drugs should inform their healthcare provider or pharmacist. In case of overdose, severe vomiting, bradycardia, respiratory depression, and muscle weakness may occur, and immediate medical treatment should be sought. Finally, this medication should be stored out of reach of children and should not be transferred to other containers for safety.

Serious side effects

Fainting, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcers, perforated duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizures, epilepsy, convulsions, intracranial hemorrhage, cerebrovascular disorders, extrapyramidal disorders (motor function disorders, ataxia, movement disorders, dystonia, tremors, involuntary movements, gait disturbances, abnormal postures, speech disorders), neuroleptic malignant syndrome (stupor, extreme muscle rigidity)

Mild side effects

• Nausea
• vomiting
• diarrhea
• appetite loss
• headache
• fatigue
• insomnia
• dizziness
• drowsiness
• anxiety

This medication should be stored in a sealed container to prevent air ingress and kept at a temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the effectiveness and prevent degradation.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle