Neurocare Tablet 5mg (Donepezil Hydrochloride Monohydrate)

Adult dose

As Donepezil Hydrochloride, take 5 mg once daily before bedtime. If unusual dreams, nightmares, or other sleep disturbances occur, morning administration may be considered. Normal levels are reached after 15 days, and after 4 to 6 weeks of administration at 5 mg, a clinical response should be evaluated, and the dose may be increased up to 10 mg. Careful attention should be paid to gastrointestinal adverse reactions when increasing the dose. Underweight women aged 85 and above should not exceed 5 mg per day.

Child dose

There is no experience using this medication in children.

This medication contains Donepezil Hydrochloride Monohydrate as its main ingredient and is used for the treatment of symptoms of Alzheimer's type dementia. This medication should not be used by those allergic to Donepezil Hydrochloride or any components of this product, women who are pregnant or may become pregnant, and nursing mothers. Additionally, it contains lactose, so individuals with lactose intolerance or related genetic disorders should avoid taking this medication. Patients with heart disease should be cautious, as this medication may stimulate the vagus nerve and cause bradycardia or arrhythmias. Those taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should use this medication carefully, as gastrointestinal problems may worsen. Patients with a history of asthma or obstructive pulmonary disease should also be cautious because bronchoconstriction and increased mucus secretion may exacerbate their symptoms. Patients with extrapyramidal disorders such as Parkinson’s disease should also be careful as the cholinergic action of this medication may worsen their symptoms. Because this medication contains Yellow 5, those allergic to this ingredient or with hypersensitivity should use it with caution. Reported side effects include heart-related issues (bradycardia, heart block, myocardial infarction, etc.), gastrointestinal problems (peptic ulcers, gastrointestinal bleeding, etc.), liver function abnormalities, seizures, movement disorders, muscle pain, shortness of breath, acute pancreatitis, acute renal failure, and sudden death. Additionally, various symptoms such as nausea, vomiting, diarrhea, dizziness, insomnia, hallucinations, anxiety, and fatigue may occur. This medication is approved only for patients with Alzheimer's type dementia and should not be used for other forms of dementia or memory decline. Treatment should be conducted under the supervision of an experienced physician, and caregivers should periodically check the status of medication administration. Patients with heart disease or electrolyte abnormalities may require an electrocardiogram, and since this medication can stimulate gastric acid secretion and cause gastrointestinal disturbances, caution is advised if these issues are present. This medication may affect driving or machinery operation abilities, so caution is needed during initiation or dosage changes. This medication can interact with several drugs, so if other medications are being taken, consulting a physician or pharmacist is essential. Caution is particularly advised when used in combination with drugs affecting CYP3A4 and CYP2D6, muscle relaxants, cholinergic drugs, anticholinergic drugs, and medications that affect cardiac conduction. It is recommended that pregnant and nursing women avoid this medication, as its safety has not been established, and consultation with a specialist is required if necessary. Safety for use in children has not been confirmed, so this medication should not be administered to children. In cases of overdose, serious symptoms such as nausea, vomiting, bradycardia, respiratory depression, and seizures may occur, and immediate medical attention is required. This medication should be kept out of reach of children and should not be transferred to another container.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• hepatitis
• liver dysfunction
• jaundice
• cerebral seizures
• epilepsy
• convulsions
• cerebral hemorrhage

Mild side effects

• Loss of appetite
• hallucinations
• agitation
• aggressive behavior
• anxiety
• insomnia
• drowsiness
• increased libido
• talkativeness
• mania

This medication should be stored in a sealed container to prevent air exposure, and the storage temperature should maintain a room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle