Lipistain Tablet 20 mg (Atorvastatin Calcium Trihydrate)

Adult dose

For hyperlipidemia, the recommended initial dose is 10 mg of atorvastatin once daily, while patients requiring greater reductions in LDL cholesterol may start with 20 mg or 40 mg once daily. This drug is administered in a dosage range from 10 to 80 mg once daily. The initial and maintenance doses should be individualized based on treatment goals and patient characteristics, and lipid levels should be analyzed within 2-4 weeks to make necessary adjustments.

Child dose

For pediatric patients (10-17 years) with heterozygous familial hypercholesterolemia, the recommended initial dose is 10 mg once daily, and the recommended maximum dose is 20 mg daily. Doses should be adjusted at intervals of 4 weeks or more.

This drug must be discontinued immediately if any abnormal symptoms occur in the muscles. This is particularly applicable in cases of muscle pain or weakness, and if there is a significant increase in creatine kinase (CK) levels in blood tests. This drug should not be administered to patients with certain diseases or those taking specific medications. For instance, it should not be used in patients with severe liver dysfunction, women who are pregnant or breastfeeding, children under 10 years old, and patients allergic to this drug or any of its components. Patients with a history of liver disease or alcoholism, patients with reduced kidney function, patients with hypothyroidism, and the elderly should use this medication cautiously and may require consultation and testing by a physician. While taking this medication, liver function and muscle status should be regularly monitored. If there are symptoms of liver dysfunction or muscle pain, weakness, fever, or fatigue, healthcare professionals should be notified immediately. This drug may interact with other medications, so caution is needed, particularly when taken with certain antibiotics, antifungals, antivirals, immunosuppressants, and some lipid-lowering agents. Patients should inform their doctor or pharmacist about any other medications they are taking. Women who are pregnant or may become pregnant should not take this medication and should use effective contraception while on this medication. Furthermore, breastfeeding women should also avoid taking this drug. The long-term safety and efficacy of this drug in children and adolescents have not been fully studied, so it should be used cautiously in patients under 18 years of age. In cases of overdose, there is no specific antidote, and appropriate treatment should be given according to the symptoms, and the condition should be monitored through liver function and muscle-related tests. This medication should be stored out of reach of children and kept in its original container for safety.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, lightning-like headache, seizures, confusion of consciousness, vision abnormalities, paralysis, urination issues.

Mild side effects

• Fatigue
• malaise
• chest pain
• peripheral edema
• exhaustion
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly closed container to protect it from air and moisture. It is also recommended to store the drug at room temperature between 1°C and 30°C. Take care to avoid placing it in excessively hot or cold environments.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle