Caduceus Tablets 5mg/10mg

Adult dose

This medication is to be administered only to adults, and the dosage should be individualized based on the efficacy and tolerability of each component, Amlodipine/Atorvastatin. Administer Amlodipine (S-Amlodipine) orally once daily, starting at 5 (2.5) mg, with dosage adjustments up to a maximum of 10 (5) mg once daily based on the patient’s response. Atorvastatin can be administered once daily in a range of 10 mg to 80 mg at any time during the day, without regard to food.

This medication should not be administered to certain patients. For instance, patients with allergies to this medication or similar components, very poor liver function, pregnant women or women who may become pregnant, nursing mothers, and patients with muscle disorders should not use this medication. Additionally, patients with severe aortic stenosis, cardiac shock, those within one month post-myocardial infarction, and unstable angina patients should also avoid this medication. This medication should be used with caution in patients with severely impaired kidney function, elderly individuals, alcoholics, and those with a history of liver disease. Patients at risk for rhabdomyolysis should have their muscle enzyme levels checked prior to administration and should use this medication carefully. Patients with acute heart failure or hypertensive crisis, those with slightly impaired liver function, and patients with severe myasthenia gravis should also be cautious. This medication generally has good tolerability; however, side effects such as flushing, fatigue, edema, palpitations, dizziness, headache, drowsiness, abdominal pain, nausea, weakness, lethargy, pain, weight gain/loss, hypotension, vasculitis, muscle tension increase, sensory loss/abnormal sensation, peripheral neuropathy, syncope, taste disturbance, tremors, extrapyramidal symptoms, erectile dysfunction, gynecomastia, changes in bowel habits, dry mouth, dyspepsia, gingival hypertrophy, gingival overgrowth, pancreatitis, vomiting, hyperglycemia, arthralgia, back pain, muscle cramps may occur. Rarely, muscle pain, rash, liver function abnormalities, and allergic reactions may occur, so if any unusual symptoms arise, one should consult a physician immediately. This medication can affect liver function, so liver function tests should be conducted regularly before and during treatment. Women who are pregnant or breastfeeding should not use this medication, and women who might become pregnant should employ appropriate contraception. The safety and efficacy of this medication in children and the elderly have not been fully established, so caution is warranted. In case of overdose, severe hypotension, shock, pulmonary edema, etc. may occur, which requires immediate emergency care. This medication may interact with several other drugs, so if taking other medications, one must inform their doctor or pharmacist. Particular caution is warranted when used concurrently with certain antibiotics, antifungals, immunosuppressants, some antihypertensives, hypoglycemic agents, and oral contraceptives, as dosage adjustments may be necessary. While taking this medication, regular checkups and adherence to physician instructions should be observed, and if unusual symptoms occur, one should consult healthcare professionals immediately.

Serious side effects

• Hives
• severe swelling (edema)
• angioedema
• chest tightness
• difficulty breathing
• cold sweats
• pallor
• toxic epidermal necrolysis
• severe allergic reactions
• severe skin abnormal reactions

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in an airtight container to prevent exposure to air or moisture, at a temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a long time.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle