Piazole Tablet 20mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Administer 10 mg orally once daily. Depending on symptoms, 20 mg may be taken once daily. Usually administered for 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms are not resolved after 8 weeks of PPI treatment, an additional 10 mg or 20 mg can be taken twice daily for an additional 8 weeks.

This medication should not be used in patients with specific allergic reactions or hypersensitivity to certain antibiotics. Pregnant or breastfeeding women should not take this medication. Patients with impaired liver function or elderly patients should use this medication cautiously, and those with a history of allergies to medications should also exercise caution. During treatment, hypersensitivity reactions such as skin rash or itching may occur; if these symptoms arise, use should be discontinued. Blood tests and liver function tests should be conducted regularly, and any abnormalities should be reported to a doctor immediately. Various side effects may appear in multiple systems including heart, digestive, neurological, respiratory, musculoskeletal, skin, eyes, and urinary systems; thus careful observation is needed if symptoms develop. Long-term use may increase the risk of osteoporosis and fractures; if necessary, bone density tests should be performed. This medication reduces gastric acid secretion, which may increase the risk of bacterial infections in the stomach, so persistent diarrhea symptoms should be reported to healthcare professionals. Driving or operating machinery may cause drowsiness; caution is needed. There may be interactions with other medications, so it is essential to inform your doctor about any other medications you are taking. This medication should be swallowed whole and not chewed or crushed, and it should be kept out of reach of children. If pregnant or breastfeeding, consult a doctor before taking this medication, as it may affect the fetus or newborn. There is no specific antidote for overdose; appropriate treatment should be administered based on the symptoms.

Serious side effects

• Urticaria
• severe swelling (edema)
• chest tightness
• difficulty breathing
• jaundice
• extreme drowsiness
• severe allergic reactions
• severe skin reactions
• breathing problems
• liver abnormalities (jaundice)

Mild side effects

• Rash
• itching
• erythrocytopenia
• leukopenia
• leukocytosis
• eosinophilia
• neutrophilia
• lymphocytopenia
• anemia
• petechiae

Store this medication in a tightly sealed container to prevent air or moisture from entering. It is recommended to keep it at room temperature between 1 and 30 degrees Celsius.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets/PTP (14 tablets/PTP × 2)