Octadipine Tablets (Amlodipine Besilate)

Adult dose

Adults: Administer 5 mg of amlodipine orally once daily, with the possibility of increasing to a maximum of 10 mg once daily based on the patient's response. Adjust doses appropriately according to age and symptoms.

This medication should not be used in certain patients. For example, it is contraindicated for those with allergies to this drug or similar drugs, nursing women, patients with severe liver dysfunction, patients with significant heart valve problems, or those in a state of shock. Caution is necessary when using this medication, especially for patients with very low blood pressure, those with severely impaired kidney function requiring dialysis, the elderly, and pregnant women or those who may become pregnant. Common side effects may include flushing, fatigue, edema, palpitations, dizziness, headaches, drowsiness, abdominal pain, and nausea. Rarely, various symptoms such as hypotension, vasculitis, neurological abnormalities, erectile dysfunction, dry mouth, liver dysfunction, skin rashes can appear, so consult a physician if symptoms are severe or persist. Patients with heart failure or impaired liver function should be particularly cautious when using this medication, as the medication's effects appear gradually and are not suitable for acute cardiac issues. There may be interactions when using this medication with several other drugs. Especially, taking it with grapefruit juice can lead to excessive effects of this medication, so it is advisable to avoid this combination. Additionally, exercise caution and monitor closely when taken with certain antibiotics or immunosuppressants under a physician's direction. The safety of this medication has not been established in pregnant or nursing women, and it is generally recommended not to use it except in special circumstances. For children, its use is only recommended in those aged 6 years and older, as its effects and safety have not been established in younger ages. Overdose of this medication can lead to severe hypotension and cardiac issues, so it's important to adhere strictly to the prescribed dosage and seek immediate medical attention in case of overdose. Washing out the stomach or administering activated charcoal may be helpful in overdose cases, and monitoring the patient's heart and respiratory status closely is necessary. Although it is known not to significantly affect driving or operating machinery, caution is needed if dizziness or drowsiness occurs.

Serious side effects

• Hives
• angioedema
• toxic epidermal necrolysis
• jaundice
• hepatitis
• severe edema
• dyspnea
• difficulty breathing
• pulmonary edema
• severe allergic reactions

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headaches
• drowsiness
• abdominal pain
• nausea
• weakness

Store this medication in a tightly sealed container to prevent air and moisture from entering. It is best to maintain a storage temperature between 1 degree and 30 degrees Celsius to safely preserve the medication's effectiveness.

Appearance

White to light yellow octagonal tablets

Package unit

30 tablets/bottle, 300 tablets/bottle