Prestin 5 mg Tablet (Amlodipine Besylate)

Adult dose

Adults: 5 mg of Amlodipine is administered orally once daily, and depending on the patient's response, it may be increased up to a maximum of 10 mg per day. Adjustments should be made based on age and symptoms.

This medication should not be used in certain patients. For example, those with allergies to this medication or similar drugs, nursing women, patients with severely impaired liver function, those with severe aortic stenosis, and individuals in shock should not take it. Additionally, caution is advised when administering this drug to patients with severe hypotension, severely impaired renal function requiring dialysis, elderly patients, and women who are pregnant or may become pregnant. Side effects may occur when taking this medication. The most common side effects include facial flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, symptoms such as hypotension, neurological abnormalities, erectile dysfunction, skin rash, and liver function abnormalities may arise, so any unusual symptoms should prompt immediate consultation with a doctor. Patients with heart failure or liver impairment should be closely monitored for the benefits and side effects of this drug, as sudden discontinuation may lead to gradual decreases in blood pressure, hence caution is advised when using it alongside other antihypertensive medications. This medication is not known to significantly impair the ability to drive or operate machinery, but caution is advised if drowsiness or dizziness occurs. Additionally, interactions with other medications may occur. Grapefruit juice, in particular, may excessively enhance the effects of this medication, so concurrent use should be avoided. When used with certain antibiotics or immunosuppressants, blood pressure may drop, or drug concentrations may change, so medical advice should be followed. Pregnant or nursing women should avoid using this medication unless absolutely necessary, as its safety has not been sufficiently confirmed; if breastfeeding, it is recommended to discontinue during the course of the medication. In children, it's recommended for use only in those aged 6 years and older, as efficacy and safety have not been established in children under 6. In cases of overdose, hypotension or tachycardia may occur, and in severe cases, shock may ensue, necessitating immediate emergency treatment. This medication is not removed by hemodialysis, so professional treatment is required in overdose situations. While taking this medication, regular consultations with a physician are recommended, and any changes in adverse reactions or symptoms should be closely monitored.

Serious side effects

• Urticaria, angioedema
• Difficulty breathing
• Jaundice
• Severe swelling
• Severe allergic reactions
• Severe skin reactions
• Liver abnormalities (jaundice)
• Severe neurological symptoms
• Significant reduction in urine output
• Swelling accompanied by elevated blood pressure

Mild side effects

• Vascular: Flushing, hypotension, vasculitis, palpitations, sinoatrial block or atrioventricular block, decreased blood pressure
• Systemic: Fatigue, swelling, weakness, lethargy, pain, weight changes, debilitation
• Central and peripheral nervous systems: Dizziness, headache, drowsiness, increased tension, sensory impairment/abnormal sensations, peripheral neuropathy, syncope, altered taste, tremor, extrapyramidal disorder
• Gastrointestinal: Abdominal pain, nausea, changes in bowel habits, dry mouth, dyspepsia, gingival hyperplasia, vomiting, diarrhea,

This medication should be stored in a tightly closed container to protect it from air and moisture. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. Proper storage helps to ensure the medication's effectiveness is preserved.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle