Pentowell Sustained Release Tablet 400 mg (Pentoxifylline)

Adult dose

Adults: Administer 400㎎ of pentoxifylline per dose orally 2-3 times daily after meals with a small amount of liquid. The dose may be adjusted as appropriate according to age and symptoms.

This medication should not be used in certain patients. For example, individuals allergic to this drug or similar drugs, patients with acute myocardial infarction, patients with severe bleeding or severe bleeding in the eyes, and patients taking ketorolac, a specific pain reliever, may be at risk if they take this medication. Additionally, patients with severe cardiac rhythm abnormalities, low blood pressure or coronary artery disease, severely impaired kidney function, severely poor liver function, patients at high risk of bleeding, and patients taking this medication alongside anticoagulants or diabetes medications should exercise particular caution while using this drug. Taking this drug can lead to a variety of side effects, such as elevated liver enzymes, low blood pressure, cardiac arrhythmias, respiratory distress, decreased blood cells, dizziness, headaches, gastrointestinal disorders, skin rashes, bleeding, allergic reactions, problems with the liver and bile ducts, and symptoms of mental instability. In particular, taking this medication at high doses may lead to more frequent symptoms such as fever, gastrointestinal discomfort, vomiting, and diarrhea, as well as the possibility of tachyarrhythmias. This medication should only be administered to patients with cerebrovascular diseases after a precise diagnosis has been made, and hypertensive patients should regularly check their blood pressure. Also, when taken with anticoagulants or diabetes medications, the risk of bleeding may increase or glucose control may be affected, so it should be taken under medical supervision. Women who are pregnant or may become pregnant, as well as nursing mothers, are advised not to take this medication for safety reasons. There is no experience with this medication in children, and elderly patients may have weakened physical functions, so careful observation of their condition should be maintained during administration. In the case of overdose, no specific antidote exists, and measures such as immediate gastric lavage or administration of activated charcoal should be taken to prevent further absorption of the drug. Finally, this medication should be kept out of the reach of children, and transferring it to other containers may lead to deterioration of quality or risk of accidents, so caution should be exercised.

• Increased aminotransferase
• hypotension
• increased BUN
• increased ALT/AST
• arrhythmia
• tachycardia
• angina
• edema
• nasal bleeding
• flu symptoms

This medication should be stored in a sealed container to protect it from air and moisture. The storage temperature should be maintained at room temperature that is not too hot or cold, and it is recommended to store it in a dark place away from direct sunlight.

Appearance

White rectangular film-coated sustained release tablet

Package unit

30 tablets/bottle, 250 tablets/bottle