S-One MP Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Adults - Treatment of gastroesophageal reflux disease (GERD): Administer 40 mg once daily for 4 weeks for erosive esophagitis. If not treated, take for an additional 4 weeks. - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily, may be administered as needed.

Children's dosage

Adolescents over 12 years - Treatment of gastroesophageal reflux disease (GERD): Administer 40 mg once daily for 4 weeks for erosive esophagitis. If not treated, take for an additional 4 weeks. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis

This medication should not be used in patients who have allergic reactions to certain ingredients or have had hypersensitivity to similar medications in the past. Additionally, since side effects or interactions may occur when used in combination with certain antibiotics or antiviral agents, it is essential to consult a physician. Pregnant or breastfeeding women must consult a specialist before using this medication, and it is safer for nursing mothers not to take it. Regular check-ups are required for long-term use, especially for patients taking it for more than one year, as health conditions like magnesium levels in the blood should be periodically monitored. This medication may increase the risk of bacterial proliferation in the gastrointestinal tract due to reduced stomach acid, so if unusual symptoms such as diarrhea persist, medical personnel should be informed immediately. Moreover, various side effects such as headache, dizziness, abdominal pain, skin rash may occur in some patients, and if symptoms are severe or persist, consultation with healthcare providers is advised. Patients with a history of heart disease or those taking certain medications should use this medication with special caution, as the risk of side effects may be increased due to drug interactions. In case of overdose, there is no specific antidote, and appropriate treatment should be sought immediately at a hospital. It should be kept out of reach of children in a safe place. Finally, it is important to adhere to the prescribed dosage and duration, and to consult a specialist immediately if any unusual symptoms arise.

Serious side effects

Urticaria, angioedema, anaphylactic reactions, shock, severe allergic reactions, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, mucous membrane hypersensitivity syndrome, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms), jaundice, hepatitis, liver failure, encephalopathy, bronchospasm, difficulty breathing, asthma attacks, severe headache, seizures, disorientation, visual disturbances, paralysis, increased blood pressure, severe symptoms.

Mild side effects

• Leukopenia
• thrombocytopenia
• agranulocytosis
• pancytopenia
• fever
• angioedema
• peripheral edema
• hyponatremia
• hypomagnesemia
• insomnia

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. Additionally, it should be kept at room temperature between 1°C and 30°C, avoiding places that are too hot or too cold.

Appearance

Pale pink round film-coated tablet

Package unit

Domestic Use: 28 tablets (14 tablets/PTP X 2) Export Use: 28 tablets (14 tablets/PTP X 2), 30 tablets/bottle