Medication info
Amloduwet Tablet 5/10mg

Amloduwet Tablet 5/10mg

Prescription medicationTablet경구
Ingredient · strength
Amlodipine Besylate›6.935mg / 1 tabletAtorvastatin Calcium Trihydrate›10.85mg / 1 tablet
Manufacturer / importer
(주)휴온스
Appearance
White oval film-coated tablets
Packaging
100 tablets/bottle, 30 tablets/bottle
Approval status
Active

MFDS item code 201402068 · Approved 2014.04.30 · Insurance code 670606900

Summary

Main use
(Hypertension, Angina) Improvement of myocardial ischemia and (cardiovascular risk) reduction of the risk of myocardial infarction and stroke
Who takes it
Adults
Adult dose
Administer 5 (2.5) mg of amlodipine (as esamlodipine) orally once daily, which may be increased to a maximum of 10 (5) mg daily depending on the patient's response. Adjust dosage appropriately according to symptoms. The recommended initial dose of atorvastatin is 10 mg once daily, but if greater reduction in LDL cholesterol levels is required, it may be started at 20 mg or 40 mg once daily.

Ingredients

Manufacturer
(주)휴온스

Efficacy & effects

(Hypertension, Angina) Improvement of myocardial ischemia and (cardiovascular risk) reduction of the risk of myocardial infarction and stroke

  • Hypertension
  • fixed closure of coronary arteries
  • coronary vasospasm
  • vasoconstriction
  • myocardial ischemia
  • angina
  • heart failure
  • low HDL cholesterol levels
  • family history of early coronary heart disease
  • retinopathy
  • albuminuria
  • type 2 diabetes
View approved original text

This medication is used for patients who need to take two drugs, amlodipine and atorvastatin, simultaneously. Amlodipine helps treat hypertension, stable angina, and myocardial ischemia caused by vasoconstriction. It also reduces the risk of hospitalization due to angina and the risk that may occur after coronary artery revascularization. Atorvastatin reduces the risk of cardiovascular diseases and is effective in preventing myocardial infarction and stroke. It is also used to improve blood lipid levels in patients with hypercholesterolemia or dyslipidemia. This medication is effectively used to maintain cardiovascular health and reduce the risk of related diseases.

How to take

Adult dose

Administer 5 (2.5) mg of amlodipine (as esamlodipine) orally once daily, which may be increased to a maximum of 10 (5) mg daily depending on the patient's response. Adjust dosage appropriately according to symptoms. The recommended initial dose of atorvastatin is 10 mg once daily, but if greater reduction in LDL cholesterol levels is required, it may be started at 20 mg or 40 mg once daily.

Precautions

It is very important not to use this medication in specific patients. First, it should not be administered to patients who have had allergic reactions to this medication or similar drugs, patients with severe liver dysfunction, patients with active liver disease, patients with obstructed bile secretion or muscle disease, pregnant women or women who may become pregnant, nursing women, patients with severe aortic stenosis, patients in shock, patients with severe hypotension, patients who have recently experienced a myocardial infarction, patients with unstable angina, and patients taking certain antiviral drugs. Additionally, it should be administered with caution to patients with severe renal dysfunction, elderly people, patients with a history of alcohol abuse or liver disease, patients at risk of developing muscle disease, patients with acute heart failure, patients in hypertensive crisis, patients with mild liver dysfunction, and those with myasthenia gravis. Various side effects may occur when taking this medication. Commonly, symptoms may include flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, muscle pain, skin rash, abnormal liver function, and allergic reactions may occur, so if any abnormal symptoms arise, you should consult a doctor immediately. This medication carries risks associated with liver dysfunction or muscle disease, so regular blood tests and liver function tests must be conducted, and symptoms such as muscle pain or weakness should be reported immediately. Pregnant or nursing women should not take this medication, and women of childbearing age should use appropriate contraception. This medication may interact with other drugs, so if you are taking any other medications, be sure to inform your doctor or pharmacist. Caution is particularly needed when taken together with certain antibiotics, antifungals, antivirals, immunosuppressants, blood pressure medications, and antidiabetic drugs. In the case of overdose, there is a risk of severe hypotension, decreased heart function, and shock, so you must go to the hospital immediately, and treatment will be conducted appropriately based on symptoms. The safety of this medication in children and the elderly has not been sufficiently confirmed, so special caution is needed for patients in these age groups. Lastly, this medication should be stored out of reach of children and not transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by coughing and fever, breathing problems, yellowing of the skin or eyes, jaundice, generalized extreme lethargy, liver abnormalities, sudden and very severe headaches

Mild side effects

  • Flushing
  • fatigue
  • swelling
  • palpitations
  • dizziness
  • headache
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
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  • lethargy
  • pain
  • weight gain/loss
  • hypotension
  • vasculitis
  • increased muscle tension
  • sensory loss/sensory disturbances
  • peripheral neuropathy
  • syncope
  • taste abnormalities
  • tremors
  • extrapyramidal symptoms
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • dyspepsia
  • gingival thickening
  • gingival hyperplasia
  • pancreatitis
  • vomiting
  • hyperglycemia
  • joint pain
  • back pain
  • muscle cramps

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container that blocks air and moisture, preferably in a cool place between 15 degrees and 30 degrees Celsius. By storing it this way, the effectiveness and safety of the medication can be maintained for a long time.

Appearance and packaging

Appearance

White oval film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.