Amloduret Tablet 10/20mg

Adult dose

This medication is administered only to adults, and the dosage should be individualized for each patient based on the effectiveness and tolerability of amlodipine/atorvastatin. Amlodipine (Es-Amlodipine): Administer orally once daily at 5 (2.5) mg, which may be increased to a maximum of 10 (5) mg daily depending on the patient's response. Adjust dosage appropriately according to symptoms. Atorvastatin: - Primary hypercholesterolemia and mixed dyslipidemia patients (Fredrickson Types IIa and IIb)

This medication should not be used in certain patients. For example, patients who are allergic to this drug or similar medications, those with severe liver dysfunction, pregnant or breastfeeding women, patients with muscle disease, severe aortic stenosis, patients in shock, patients within one month post-myocardial infarction, patients with unstable angina, and those taking certain hepatitis treatments should not take this medication. Additionally, patients with severely impaired kidney function, the elderly, alcoholics, those with a history of liver disease, and patients at high risk for muscle damage should use this drug cautiously. In such cases, muscle damage indicators should be examined before starting treatment, and the patient's condition should be closely monitored during administration. This medication is generally well-tolerated, but symptoms such as flushing, fatigue, edema, palpitations, dizziness, headache, nausea, weakness, lethargy, pain, weight gain/loss, hypotension, vasculitis, muscle tension, sensory loss/abnormal sensations, peripheral neuropathy, fainting, altered taste, tremors, extrapyramidal disorders, erectile dysfunction, gynecomastia, changes in bowel habits, dry mouth, indigestion, gingival hypertrophy, gum hyperplasia, pancreatitis, vomiting, high blood sugar, joint pain, low back pain, and muscle cramps may occur. Rarely, muscle pain, liver function abnormalities, allergic reactions, skin rashes, and blood abnormalities have been reported, so if these symptoms occur, consult a doctor immediately. Regular liver function tests should be conducted if there are any liver function abnormalities or signs of hepatitis, and if liver function worsens, the use of this medication should be discontinued. Additionally, if symptoms such as muscle pain or weakness occur, they should be reported immediately, as severe cases may require discontinuation of the medication. This medication can interact with other drugs, so caution is necessary, especially when taken with certain antibiotics, antifungals, immunosuppressants, some antivirals, and grapefruit juice. If there are co-administered drugs, medical personnel must be informed, and dosage adjustments or monitoring may be necessary. Women who are pregnant or may become pregnant should not take this medication, and if pregnancy is confirmed during use, it should be stopped immediately and a doctor should be consulted. Breastfeeding women should also not take this medication, and breastfeeding should be stopped if taking this medication. Safety for children and the elderly has not been adequately established, so use with caution is necessary. In case of overdose, serious symptoms such as low blood pressure, heart rhythm disturbances, and shock may occur, so immediate emergency treatment is required, and medical personnel should closely monitor cardiovascular function and provide appropriate treatment.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with coughing and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, and urination.

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is advisable to keep the storage temperature between 15 to 30 degrees Celsius.

Appearance

Blue oval film-coated tablet

Package unit

100 tablets/bottle, 30 tablets/bottle