Clopidogrel Tablets (Clopidogrel Sulfate)

Adult dose

1. Patients with ischemic stroke, myocardial infarction, or peripheral arterial disease: Administer clopidogrel 75 mg orally once daily. 2. Patients with acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction): On the first day of treatment, start with a loading dose of 300 mg of this drug once daily, followed by an oral maintenance dose of 75 mg once daily. Aspirin 75 ∼ 325 mg should be administered concomitantly with this drug once daily. 3. Patients with atrial fibrillation: Administer 75 mg of this drug orally once daily. Aspirin 75 ∼ 100 mg should be administered concomitantly with this drug once daily. This drug may be administered with or without food.

This medication is designed to prevent blood clot formation by inhibiting platelet aggregation in the blood. Before taking this medication, if you have a genetically reduced function of the specific enzyme CYP2C19, the effectiveness of this medication may be diminished; therefore, you should consult with your doctor to decide on the appropriate treatment method. Additionally, taking this medication together with drugs that increase the activity of the CYP2C19 enzyme may increase the concentration of the active ingredient of this medication and raise the risk of bleeding, so it is advisable not to use them in combination. Patients who are allergic to this medication or its components, currently have bleeding, have severe liver damage, are breastfeeding women, or have certain genetic diseases such as lactose intolerance should not use this medication. Patients at high risk of bleeding, such as those with bleeding disorders or those taking other medications that may cause bleeding, and patients scheduled for surgery should use this medication with caution, and if any bleeding symptoms occur, they should immediately inform medical personnel. Long-term use of this medication may result in various side effects such as bleeding, gastrointestinal disorders, skin rashes, and reduced blood cell counts; therefore, should any abnormal symptoms appear, you should consult a doctor right away. Women who are pregnant or breastfeeding should consult a doctor before taking this medication, as there may be an increased risk of bleeding during delivery. The safety and efficacy of this medication in children have not been fully established, and elderly patients may be at increased risk of bleeding due to decreased bodily functions; therefore, caution is needed when taking this medication. In cases of overdose, the risk of bleeding may increase, and there is no specific antidote, so treatment such as platelet transfusion may be necessary if needed. During treatment with this medication, attention should be paid to interactions with other medications, especially when combined with drugs that may increase the risk of bleeding, it is advisable to consult a doctor. Lastly, this medication should be kept out of reach of children and should not be transferred to other containers for safety.

Hemorrhage, gastrointestinal bleeding, purpura, contusion, hematoma, nasal bleeding, hematoma, hematuria, intraocular hemorrhage, intracranial hemorrhage, severe neutropenia, agranulocytosis, aplastic anemia, thrombocytopenia, abdominal pain, dyspepsia, diarrhea, nausea, rash, pruritus, urinary tract infection, headache, dizziness, chest pain, accidental injury, influenza-like illness, pain, fatigue, edema, hypertension, depression, respiratory distress, rhinitis, bronchitis, cough, urinary tract infection, decreased motor function, tremors, speech disorder, abnormal gait, hyperkinesia, ataxia, sensory disturbances, constipation, vomiting, ulcer, abdominal pain, loss of appetite, thirst, dysphagia, tongue disorders, insomnia, depression, forgetfulness, anxiety, hypersomnia, abnormal thoughts, abnormal behavior, rigidity, weight loss, weight gain, facial flushing, weakness, syncope, purpura disease, melena, thrombocytopenia, anemia, pneumonia, sinusitis, visual disturbances, visual field defects, dryness of the eyes, transient blindness, congestion, tinnitus, taste disturbances, urinary difficulties, polyuria, non-protein nitrogen increase, uremia, increased blood urea nitrogen, hypoglycemia, hyperuricemia, increased liver enzymes, elevated ALT, abnormal liver function, leg edema, arrhythmia, bradycardia, palpitations, contact dermatitis, gynecomastia, elevated prostate-specific antigen, allergic symptoms, ischemic necrosis, gastritis, hemorrhagic gastroenteritis, duodenal ulcer, gastric ulcer, perforated gastric ulcer, upper gastrointestinal tract bleeding, distension, hyperbilirubinemia, infectious hepatitis, fatty liver, hemorrhagic arthropathy, hematuria, hemoptysis, retroperitoneal hemorrhage, surgical wound hemorrhage, pulmonary hemorrhage, vasculitis, hypotension, bronchial spasm, interstitial pneumonia, eosinophilic pneumonia, colitis, pancreatitis, stomatitis, hepatitis, acute liver failure, petechial eruption, erythematous or desquamative skin rash, urticaria, itching, angioedema, vesicular dermatitis, drug-induced hypersensitivity syndrome, drug rash with eosinophilia and systemic symptoms, eczema, lichen planus, arthralgia, arthritis, myalgia, glomerulonephritis, gynecomastia, fever, abnormal liver function tests, increased blood creatinine, cholecystitis, hematemesis, spinal hematoma

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and should be kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and ensure safe use.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle