Medication info

Racidin Tablet 150mg (Ranitidine Hydrochloride)

Prescription medication경구Expired
Ingredient · strength
Ranitidine Hydrochloride›168mg / 1 tablet
Manufacturer / importer
(주)인트로바이오파마
Appearance
White circular film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Expired

MFDS item code 201400868 · Approved 2014.02.26

This product's status changed to Expired on 2024.02.26. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of gastric ulcer and gastric mucosal lesions, treatment of Zollinger-Ellison syndrome
Who takes it
Adults · Children
Adult dose
As ranitidine, the dose is 150mg orally twice daily, in the morning and at bedtime. Gastric and duodenal ulcers: 150mg orally twice daily or 300mg once daily at bedtime. Patients with duodenal ulcers may take 300mg orally twice daily, in the morning and at bedtime. For recurrent ulcer patients, 150mg is used once daily at bedtime as maintenance therapy. Gastroesophageal reflux disease
Child dose
Pediatric patients aged 8-18 years can be administered 150mg (2mg per kg of body weight) once or twice daily.

Ingredients

Manufacturer
(주)인트로바이오파마

Efficacy & effects

Improvement of gastric ulcer and gastric mucosal lesions, treatment of Zollinger-Ellison syndrome

  • Gastric ulcer
  • duodenal ulcer
  • Zollinger-Ellison syndrome
  • gastroesophageal reflux disease
  • Mendelson's syndrome
  • postoperative ulcer
  • gastric ulcer due to NSAID administration
  • gastric mucosal lesions
  • erosion
  • bleeding
  • erythema
  • edema
View approved original text

This medication is used for the treatment of gastric and duodenal ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease. It is also used as a preoperative medication to prevent Mendelson's syndrome and helps in the treatment of gastric and duodenal ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs). It is effective in improving gastric mucosal lesions during acute exacerbations of acute and chronic gastritis, and upper gastrointestinal bleeding (such as peptic ulcer, acute stress ulcer, etc.). This medication promotes the recovery of gastric mucosal damage such as erosion, bleeding, erythema, and edema, thereby improving gastric health.

How to take

Adult dose

As ranitidine, the dose is 150mg orally twice daily, in the morning and at bedtime. Gastric and duodenal ulcers: 150mg orally twice daily or 300mg once daily at bedtime. Patients with duodenal ulcers may take 300mg orally twice daily, in the morning and at bedtime. For recurrent ulcer patients, 150mg is used once daily at bedtime as maintenance therapy. Gastroesophageal reflux disease

Child dose

Pediatric patients aged 8-18 years can be administered 150mg (2mg per kg of body weight) once or twice daily.

Precautions

This medication should not be used in patients with hypersensitivity to any of its components. Additionally, due to the presence of lactose hydrate, patients with galactose intolerance, lactase deficiency, and glucose-galactose malabsorption should not take this medication. For patients with impaired renal function, the dosage should be adjusted or the dosing interval extended to avoid increased blood concentration. Patients with liver function problems or a history of drug hypersensitivity, as well as elderly patients, should take it with caution. In cases of concurrent use of NSAIDs, elderly patients or those with a history of peptic ulcers should have their condition regularly monitored. Patients with a history of acute porphyria should avoid this medication as it may trigger seizures. This medication may rarely cause severe allergic reactions such as anaphylactic shock, urticaria, angioedema, rash, fever, bronchospasm, and hypotension; if any abnormal symptoms appear, immediately discontinue use and consult a healthcare professional. Blood-related adverse reactions can include neutropenia, leukopenia, and thrombocytopenia, so it is important to undergo blood tests if symptoms like fatigue, bleeding, or fever occur. Transient liver dysfunction may occur; discontinue use immediately if symptoms of jaundice or hepatitis appear. Caution is also needed as changes in heart rate or vascular issues have been reported rarely. Gastrointestinal symptoms can include constipation, nausea, vomiting, abdominal pain, and diarrhea. Neurological symptoms such as dizziness, drowsiness, headache, insomnia, confusion, and hallucinations may occur and require caution, especially in patients with impaired renal function. Endocrine disorders such as gynecomastia, erectile dysfunction, and decreased libido have also been reported. Musculoskeletal issues can include arthralgia, myalgia, and rarely rhabdomyolysis; any abnormal symptoms should be discussed with a healthcare provider immediately. Skin rashes or alopecia may rarely occur. If this medication does not provide therapeutic effects, it is advisable to switch to other treatment methods, and regular monitoring of blood, liver, and kidney function should be conducted. Elderly patients, those with chronic lung diseases, diabetes, and immunocompromised individuals should be cautious as the risk of pneumonia may increase. This medication can interact with other drugs, so especially when taking anticoagulants like warfarin, frequent monitoring of blood coagulation status is necessary. When taken with sucralfate, absorption may be reduced, so a spacing of more than 2 hours between doses is recommended. Women who are pregnant or may become pregnant should only use this medication if its benefits are deemed to outweigh its risks. Nursing women should also use it only when necessary, as this medication may be excreted in breast milk. Safety in pediatric patients has not been fully established, so caution is needed for use. This medication can cause false positives in urine protein tests, so care should be taken with testing methods. In case of overdose, appropriate treatment such as vomiting and gastric lavage should be implemented, and blood dialysis may be considered if necessary. Keep this medication out of reach of children, and do not transfer it to another container for safety. This medication may mask symptoms of gastric cancer; therefore, patients over middle age who have recently developed symptoms of gastric ulcer or dyspepsia should verify the presence of malignancy before use. For long-term use, it is advisable to have an eye examination for ocular health.

Side effects and when to seek care immediately

Serious side effects

  • Anaphylactic shock
  • urticaria
  • severe swelling (angioedema)
  • chest tightness
  • difficulty breathing
  • chest pain
  • hypotension
  • vasculitis
  • acute pancreatitis
  • jaundice
Show 16 more
  • altered consciousness
  • seizures
  • muscular spasms
  • acute interstitial nephritis
  • Stevens-Johnson syndrome
  • Lyell’s syndrome
  • aplastic anemia
  • heart block
  • severe edema
  • hypertension
  • thrombocytopenia
  • leukopenia
  • aplastic anemia
  • agranulocytosis
  • pancytopenia
  • acquired immune

Mild side effects

Urticaria, rash, angioedema, fever, bronchospasm, hypotension, chest pain, vascular edema, neutropenia, elevation of serum creatinine, leukopenia, thrombocytopenia, myelosuppression, aplastic anemia, agranulocytosis, pancytopenia, generalized malaise, weakness, subcutaneous and mucosal bleeding, fever, temporary liver function abnormalities (elevation of AST, ALT, γ-GTP, ALP), bradycardia, heart block, tachycardia, blood

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that does not allow light to enter. Additionally, it is best to store the medication at room temperature between 1 to 30 degrees Celsius. This will help maintain its effectiveness and prevent degradation.

Appearance and packaging

Appearance

White circular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.