Olostat Tablet 20/20 mg (Olmesartan Medoxomil, Rosuvastatin)

Adult dose

The recommended initial dose of olmesartan medoxomil for adults is 10 mg once daily, which can be taken without regard to meals. If blood pressure is not well controlled, the dose may be increased to 20 mg once daily, with a maximum allowable increase up to 40 mg once daily. Elderly patients and those with mild liver impairment do not require dose adjustments, while the maximum dosage for patients with kidney impairment is 20 mg once daily. The initial dose of rosuvastatin is 5 mg once daily.

Child dose

Safety and efficacy in children under 18 years are not established.

This drug may cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to any ingredient of this medication, women who are pregnant or nursing, patients with severely impaired kidney or liver function, and those with specific muscle diseases should not take this medication. Extreme caution should be exercised in patients with very low blood pressure or unstable kidney function as using this drug may lead to lowered blood pressure and worsened kidney function. Symptoms such as muscle pain, muscle weakness, or myopathy may occur, so if these symptoms arise, patients should immediately inform healthcare personnel and may need to discontinue medication if necessary. This drug can affect liver function, so liver function tests should be conducted regularly before and during treatment, particularly in patients with a history of liver disease. Drug interactions may occur, so patients must inform healthcare personnel of all medications currently being taken. Elderly patients or those with impaired kidney function may experience an increased concentration of this drug in their bodies, necessitating dose adjustments and careful monitoring. In the case of overdose, a decrease in blood pressure or arrhythmias may occur, necessitating immediate medical attention. Since there is no specific antidote, treatment will be symptomatic. The safety and efficacy of this medication have not been thoroughly established for children under 18, so it is advisable not to use it in this age group. During treatment, patients should avoid alcohol, and be cautious when engaging in activities that could be dangerous, such as driving or operating machinery, as dizziness or drowsiness may occur.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, vision disturbances, paralysis, urination changes.

Mild side effects

Headache, dizziness, sensory impairment, drowsiness, gastroesophageal reflux, constipation, cavities, dyspepsia, gastric ulcers, gastritis, gastroenteritis, musculoskeletal stiffness, atrial fibrillation, hypoglycemia, chest pain, palpitations, hypercholesterolemia, hyperlipidemia, hyperuricemia, arthralgia, arthritis, myalgia, rash, itching, vomiting, chronic malabsorption syndrome-like intestinal disease, abdominal pain, diarrhea, epistaxis, upper respiratory infection, cough, hypertension, thrombocytopenia, hair loss, fatigue.

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. The recommended storage temperature is room temperature between 1 to 30 degrees Celsius. This helps to maintain the drug's efficacy and safety.

Appearance

Pink, round, film-coated tablets

Package unit

30 tablets/PTP[((10 tablets/PTP)x3)], 30 tablets/bottle