Elosuva Tablet 10 mg (Rosuvastatin Calcium (Unprocessed))

Adult dose

This medication can be administered once daily at any time without regard to meals. The initial dose is 5 mg once daily; if greater LDL cholesterol reduction is required, the maintenance dose can be adjusted. The maintenance dose is typically 10 mg once daily, with most patients being managed at this dose. The maintenance dose should be adjusted appropriately based on LDL cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years), the dosage is administered once daily within the range of 5 to 20 mg. There is no clinical data on administering doses higher than 20 mg in pediatric patients.

This medication should not be administered to patients with certain allergies. It should also not be given to patients with severe liver dysfunction or unexplained elevations in liver enzymes. Patients with muscle disorders or muscle damage, and those taking cyclosporine, a specific immunosuppressant, should not use this medication. Patients with significantly reduced kidney function and women who are pregnant, breastfeeding, or of childbearing potential should consult a physician before taking this medication. In particular, high-dose administration is prohibited for patients at high risk of muscle disorders. Additionally, this medication contains lactose and should not be administered to patients with lactose intolerance or related genetic disorders. Caution is warranted for patients who have a history of excessive alcohol consumption or liver disease, and regular liver function tests should be conducted before and during treatment. If symptoms such as muscle pain or weakness occur, the physician should be notified immediately, and in severe cases, the medication should be discontinued. Additionally, caution is needed for patients with impaired renal function or hypothyroidism, elderly patients, and those with alcohol abuse, as they are at higher risk for muscle-related side effects. This medication may interact with certain drugs; patients taking other medications should inform their healthcare provider. In particular, the risk of muscle side effects may increase when used in combination with certain antiviral agents, immunosuppressants, antifungal agents, antibiotics, and fibric acid derivatives. During pregnancy, it may be harmful to the fetus, so proper contraception must be practiced, and women who are pregnant or planning to become pregnant should not use this medication. Nursing mothers should also avoid taking this medication, and if pregnancy is confirmed during treatment, it must be discontinued immediately. There are no specific antidotes for overdose, so treatment should be symptomatic along with liver and muscle function tests. This medication does not significantly affect driving or machine operation, but dizziness may occur, so caution is advised. Regular checks of liver and muscle health during treatment are important.

Serious side effects

Allergic reactions including urticaria and angioedema, severe swelling, tightness in the chest, difficulty breathing, respiratory distress, asthma attacks, Stevens-Johnson syndrome, Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), jaundice, hepatitis, severe muscle weakness, ocular myasthenia, immune-mediated necrotizing myopathy, rhabdomyolysis, acute renal failure, oliguria, severe edema, pallor, severe rash with fever, blisters, blood

Mild side effects

Headache, dizziness, constipation, nausea, abdominal pain, itching, muscle pain, weakness, diarrhea, rash, hematuria, fatigue, numbness, sensory disturbances, chest discomfort, loss of appetite, abdominal bloating, fainting, generalized pain, muscle cramps, gout, erectile dysfunction, thrombocytopenia, amnesia, peripheral neuropathy, cough, increased serum creatinine, depression, sleep disturbances, sexual dysfunction, gynecomastia, cognitive impairment (memory decline, forgetfulness, confusion)

This medication should be stored in a tightly closed container that does not allow air or moisture to enter. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature.

Appearance

Pink round film-coated tablet

Package unit

Bottle - 30 tablets/bottle