Rosunex Tablets 20mg (Rosuvastatin Calcium)

Adult dosage

The initial dose of this medication is 5 milligrams once daily, and it may be adjusted to 10 milligrams or a maximum of 20 milligrams at intervals of 4 weeks or more as needed. It can be taken at any time of the day, regardless of meals. Dosage adjustment is not necessary for elderly patients and those with mild to moderate renal impairment. The recommended starting dose for Asian patients and those susceptible to myopathy is 5 milligrams.

This drug should not be used in certain patients. For instance, it should not be administered to those who are allergic to any of the components of this drug, have active liver disease, or have muscular diseases. Additionally, it should be avoided in women who are severely renal impaired, pregnant, or breastfeeding, as well as in fertile women who do not use appropriate contraception. High doses are prohibited for patients at high risk for muscle diseases. This drug should be used with caution in patients who consume large amounts of alcohol or have a history of liver disease, and liver function tests should be conducted regularly before and during treatment. Muscle pain, myopathy, and occasionally serious muscle damage such as rhabdomyolysis can occur, so patients should immediately inform their healthcare provider if they experience any unusual muscle symptoms. Particularly in cases with risk factors for muscle damage such as renal impairment, hypothyroidism, family history of genetic muscle diseases, elderly patients, and alcohol abuse, more caution is needed. This drug can also affect liver function, so it should be stopped immediately if symptoms of liver damage or abnormal blood tests appear. It contains lactose, so patients with genetic issues such as lactose intolerance should not use this medication. There may be interactions with other medications, so it is crucial to inform healthcare providers about any current medications. When combined with certain medications, the blood concentration of this drug may increase, raising the risk of side effects. It should not be used during pregnancy or breastfeeding, and women of childbearing age should ensure proper contraception is utilized. In case of overdose, there is no specific antidote, and treatment should be based on symptoms, along with monitoring liver function and muscle enzyme levels. Caution is needed when driving or operating machinery as dizziness may occur. During the course of taking this drug, adverse reactions may include headache, dizziness, dyspepsia, muscle pain, and liver function abnormalities; these symptoms should be discussed with a healthcare provider if they persist or worsen.

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS) with eosinophilia, rhabdomyolysis, myopathy, immune-mediated myopathy, acute renal failure, oliguria, headache (in cases of severe headache), chest tightness, difficulty breathing, respiratory distress, jaundice, liver failure, fatal liver failure, disorientation, visual disturbances, paralysis, extreme edema associated with increased blood pressure

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• diarrhea

This medication should be stored in a tightly closed container to prevent air and moisture exposure, and it is advisable to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication for a longer period.

Appearance

Pink round film-coated tablets

Package unit

28 tablets/PTP